AUTHOR=Dong Xinlei , Hao Xiaomin , Wen Jian , Yan Qinfeng , Ma Kaixuan , Liu Qingguo , Li Juan , Zhang Lili 

TITLE=Study on the mechanism of acupuncture to improve mild cognitive impairment in hypertension by regulating intestinal microbiome

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 18 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1495384

DOI=10.3389/fnins.2024.1495384

ISSN=1662-453X

ABSTRACT=High blood pressure is a significant risk factor for cardiovascular diseases and is linked to an increased risk of mild cognitive impairment (MCI). The lack of effective treatments for these conditions highlights the urgent need for novel therapeutic approaches. Recent research suggests that the gut microbiota-brain-gut axis plays a crucial role in the pathogenesis of hypertension and MCI by regulating the nervous, endocrine, and immune systems. Acupuncture, an established therapeutic modality, has shown promise in influencing the course of hypertension and MCI by modulating the gut microbiota. This review aims to summarize the mechanistic relationships between the gut microbiome, hypertension, and MCI, and to explore the potential of acupuncture as a treatment strategy for managing Mild cognitive impairment in Hypertension concurrently.