AUTHOR=Zhang Wenxin , Zhang Yiping , Sun Liqian , Zhang Yupei , Shang Xuequn TITLE=Knowledge concept recognition in the learning brain via fMRI classification JOURNAL=Frontiers in Neuroscience VOLUME=Volume 19 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1499629 DOI=10.3389/fnins.2025.1499629 ISSN=1662-453X ABSTRACT=Knowledge concept recognition (KCR) aims to identify the concepts learned in the brain, which has been a longstanding area of interest for learning science and education. While many studies have investigated object recognition using brain fMRIs, there are limited research on identifying specific knowledge points within the classroom. In this paper, we propose to recognize the knowledge concepts in computer science by classifying the brain fMRIs taken when students are learning the concepts. More specifically, this study made attempts on two representation strategies, i.e., voxel and time difference. Based on the representations, we evaluated traditional classifiers and the combination of CNN and LSTM for KCR. Experiments are conducted on a public dataset collected from 25 students and teachers in a computer science course. The evaluations of classifying fMRI segments show that the used classifiers all can attain a good performance when using the time-difference representation, where the CNN-LSTM model reaches the highest accuracy. This research contributes to the understanding of human learning and supports the development of personalized learning.