AUTHOR=Brown Shael , Farivar Reza 

TITLE=The topology of representational geometry

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 19 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1597899

DOI=10.3389/fnins.2025.1597899

ISSN=1662-453X

ABSTRACT=Representational similarity analysis (RSA) is a powerful tool for abstracting and then comparing neural representations across brains, regions, models and modalities. However, typical RSA analyses compares pairs of representational dissimilarities to judge similarity of two neural systems, and we argue that such methods cannot capture the shape of representational spaces. By leveraging tools from computational topology which can probe the shape of high-dimensional data, we augment RSA to be able to detect more subtle yet real differences and similarities of representational structures. This new method could be used in conjunction with regular RSA in order to make distinct, complementary inferences about neural function.