AUTHOR=Folwarski Marcin , Kłęk Stanisław , Zoubek-Wójcik Agata , Szafrański Waldemar , Bartoszewska Lidia , Figuła Krzysztof , Jakubczyk Marlena , Jurczuk Anna , Kamocki Zbigniew , Kowalczyk Tomasz , Kwella Bogna , Matras Przemysław , Sonsala-Wołczyk Joanna , Szopiński Jacek , Urbanowicz Krystyna , Zmarzły Anna TITLE=Foods for Special Medical Purposes in Home Enteral Nutrition-Clinical Practice Experience. Multicenter Study JOURNAL=Frontiers in Nutrition VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.906186 DOI=10.3389/fnut.2022.906186 ISSN=2296-861X ABSTRACT=Background: Enteral nutrition (EN) with foods for special medical purposes (FSMP) is recommended for most patients on home enteral nutrition (HEN). Although there are disease-specific guidelines for energy, protein, and micronutrient provision only a few studies are showing real-life experience in the long-term use of FSMP. Methods: In a multicenter study the influence of the FSMP composition and administration technique (bolus vs continuous) on protein and energy provision in HEN was analyzed. Provision of vitamins and minerals was compared to recommended daily allowance (RDA) and upper tolerable limit (UL). Results: 772 patients on HEN, mostly (88.6%) with oncological and neurological diseases were enrolled. Patients on standard FSMP received less protein and energy than those on hypercaloric and protein-enriched despite receiving higher volumes of EN (p<0.05). No differences were observed in jejunal feeding with oligomeric vs polymeric FSMP in terms of energy, protein, and volume. Continuous gastric feeding provided more protein, energy and volume vs bolus feeding. 50.5%, 49%, 21.8%, 64.3%, 60% of patients received less than 100% RDA of Vitamin D, B3, K, B5, B9. 80.2%, 99%, 98%, 67%, 87%, 99% and 43% received less than 100% RDA of Sodium, Potassium, Chloride, Calcium, Magnesium, Fluoride, and Iodine. 43.63% of cancer and 49.9% of neurological patients received less than 1g/kg/day of protein and 51.7% of cancer and 55.5% of neurological received less than 25kcal/kg/day. Conclusions: Awareness of the available compositions of FSMP and advantageous profiles of specific diets may lead to the implementation of recommendations for EN. HEN professionals need to analyze all the requirements for the patients and provide a more tailored matching of nutritional support.