AUTHOR=Tang Xiaolong , Liu Hanguang , Xiao Yuan , Wu Lei , Shu Peng 

TITLE=Vitamin C Intake and Ischemic Stroke

JOURNAL=Frontiers in Nutrition

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.935991

DOI=10.3389/fnut.2022.935991

ISSN=2296-861X

ABSTRACT=Vitamin C is an essential micronutrient with important antioxidant properties. Ischemic stroke is a major public health challenge. Extensive evidence has demonstrated that vitamin C has protective effects in preventing cardiovascular disease (CVD), and there is a close relationship between vitamin C intake and ischemic stroke. Results from this umbrella review emphasize the relationship between vitamin C and ischemic stroke from four perspectives: cellular mechanisms, animal experiments, clinical trials, and cohort studies.