AUTHOR=Sadeghi Omid , Eshaghian Niloofar , Keshteli Ammar Hassanzadeh , Askari Gholamreza , Esmaillzadeh Ahmad , Adibi Peyman TITLE=Association of combined healthy lifestyle with general and abdominal obesity JOURNAL=Frontiers in Nutrition VOLUME=Volume 10 - 2023 YEAR=2024 URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1332234 DOI=10.3389/fnut.2023.1332234 ISSN=2296-861X ABSTRACT=Background: Data linking joint healthy lifestyle factors to general and abdominal obesity are scarce, in particular in the Middle East. The aim of this cross-sectional was to examine the association of combined healthy lifestyle factors with general and abdominal obesity in a large population of Iranian adults.This cross-sectional study was done on 3,172 Iranian adults aged ≥18 years. We constructed healthy lifestyle score using information on dietary intakes, physical activity, smoking status, and psychological distress. To evaluate components of healthy lifestyle, we applied a validated 106-item semi-quantitative food frequency questionnaire (FFQ), General Practice Physical Activity Questionnaire (GPPAQ), General Health Questionnaire (GHQ), and other pre-tested questionnaires. General obesity was defined as having a body mass index (BMI) ≥30 kg/m 2 and abdominal obesity as a waist circumference (WC) of ≥102 cm in men and ≥88 cm in women.Results: Mean age of participants was 36.54 ± 7.97 years. General and abdominal obesity were prevalent among 8.7% and 21.5% of study participants, respectively. Linear analysis showed a significant positive relationship between healthy lifestyle score and BMI among men (β: 0.30, 95% CI: 0.05, 0.54). However, no significant association was found between healthy lifestyle and abdominal obesity in men. Among women, one score increase in healthy lifestyle score was associated with a reduction of 0.65 cm in WC. In terms of individual components of healthy lifestyle, we found that low-distressed women had lower odds of abdominal obesity compared with high-distressed women.We found a significant inverse association between healthy lifestyle and WC among women. However, healthy lifestyle was positively associated with BMI among men.