AUTHOR=Hao Xuanyu , Liu Gang , Li Dongyang 

TITLE=Association of healthy eating index-2015 and overactive bladder: a cross-sectional study

JOURNAL=Frontiers in Nutrition

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1400398

DOI=10.3389/fnut.2024.1400398

ISSN=2296-861X

ABSTRACT=Objective: The aim of this cross-sectional study was to investigate the association of HEI-2015 and overactive bladder (OAB) in a large population.
Methods: Data was retrieved from the National Health and Nutrition Examination Survey (NHANES) 2005-2020 datasets. Univariate and multivariate logistic regression were performed to evaluate the association between HEI-2015 and OAB. The restricted cubic spline (RCS) model was conducted to investigate the dose-response relationship. 
Results: Totally, this study included 29,206 participants with 6,184 OAB patients among them. The higher continuous HEI-2015 value was independently associated with lower OAB incidence (OR: 0.87; 95%CI: 0.78, 0.98). Similarly, the highest quartile categorical HEI-2015 was significantly associated with a lower OAB odds (OR:0.72; 95%CI:0.52, 0.99) when compared with the lowest quartile. The RCS  curve also showed a favourable non-linear dose-response relationship between HEI-2015 and OAB.
Conclusions: A higher HEI-2015 had an favorable association with OAB and there was a non-linear dose-response relationship between them. We suggest adherence to the US diet recommendation as a potential behavioral prevention of OAB. Large-scale long term prospective cohort studies across various regions are needed to verify the findings of this paper.