AUTHOR=Wu He , Chen Xiyi , Shi Zhengqing , Liu Jieyu , Meng Ziqi , Zheng Chenguo , Zhou Chongjun 

TITLE=The L-shaped relationship between composite dietary antioxidant index and sarcopenic obesity in elderly adults: a cross-sectional study

JOURNAL=Frontiers in Nutrition

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1428856

DOI=10.3389/fnut.2024.1428856

ISSN=2296-861X

ABSTRACT=Background: This study aimed to examine the independent and combined associations of Composite Dietary Antioxidant Index (CDAI) with sarcopenic obesity (SO) using the National Health and Nutrition Examination Survey (NHANES) database.Methods: Data was gathered from NHANES between 2001 and 2004. To examine the relationship between CDAI and the occurrence of SO, multiple logistic regression analyses were performed.Subgroup analyses were performed to demonstrate stability of results. Restricted cubic splines were utilized to examine the non-linear correlations.Results: A total of 2,333 individuals were included in the study. In the multivariate logistic regression crude model, we revealed an odds ratio of 0.928 [95% confidence interval (CI), 0.891-0.965, P < 0.001] for the correlation between CDAI and SO. The ORs were 0.626 (95% CI, 0.463-0.842) and 0.487 (95% CI, 0.354-0.667) for CDAI tertiles 2 and 3, respectively (p for trend < 0.001), after full adjusted. The subgroup analysis findings demonstrated a reliable and enduring connection between CDAI and SO across various subgroups. However, the strength of the correlation between CDAI and SO was significantly affected by diabetes (p for interaction = 0.027). Moreover, restricted cubic spline analysis revealed a L-shaped relationship.Conclusions: The present study identified an L-shaped correlation between CDAI and SO in the elderly demographic. The implications of these findings were significant for future studies and the formulation of dietary guidelines.