AUTHOR=Li Jianfen , Jiang Chaohui , Wu Lingfeng , Tian Jiangyan , Zhang Bin 

TITLE=Dietary selenium intake and sarcopenia in American adults

JOURNAL=Frontiers in Nutrition

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1449980

DOI=10.3389/fnut.2024.1449980

ISSN=2296-861X

ABSTRACT=The relationship between dietary selenium intake and sarcopenia remains poorly understood. This study investigates the associations between dietary selenium intake and sarcopenia among American adults.This cross-sectional study analyzed data from 19,696 participants in the National Health and Nutrition Examination Survey (NHANES) for 1999-2006 and     2011-2018. Appendicular muscle mass, assessed using dual-energy X-ray absorptiometry and adjusted for body mass index, was used as a marker for sarcopenia. Dietary selenium intake was evaluated through the 24-hour dietary recall system, and the study accounted for the complex sampling design and dietary sample weights.Results: Among the 19,696 participants, the prevalence of sarcopenia was 8.46%.Compared to the lowest quintile of dietary selenium intake (Q1, <80.10μg/day), the odds ratios for sarcopenia in the second quintile (Q2, 80.10-124.61μg/day) and the third quintile (Q3, >124.61μg/day) were 0.80 (95% confidence interval [CI]: 0.70-0.92, p=0.002) and 0.61 (95% CI: 0.51-0.73, p<0.001), respectively. A negative relationship was observed between dietary selenium intake and sarcopenia (nonlinear: p=0.285).Furthermore, sensitivity analyses revealed a robust association after further adjusting for blood selenium levels.The results suggest an inverse association between dietary selenium intake and sarcopenia among American adults.