<?xml version="1.0" encoding="utf-8"?>
    <rss version="2.0">
      <channel xmlns:content="http://purl.org/rss/1.0/modules/content/">
        <title>Frontiers in Nutrition | New and Recent Articles</title>
        <link>https://www.frontiersin.org/journals/nutrition</link>
        <description>RSS Feed for Frontiers in Nutrition | New and Recent Articles</description>
        <language>en-us</language>
        <generator>Frontiers Feed Generator,version:1</generator>
        <pubDate>2026-05-13T11:00:37.844+00:00</pubDate>
        <ttl>60</ttl>
        <item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1805016</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1805016</link>
        <title><![CDATA[The cholesterol, high-density lipoprotein, and glucose index as a metabolic-nutritional biomarker for risk stratification in hospitalized heart failure patients]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Zefan Huang</author><author>Liusheng Xu</author><author>Jinhui Zhang</author><author>Kefeng Lu</author><author>Jun Xu</author><author>Yichen Fang</author><author>Wei Ni</author><author>Ping Zhang</author><author>Tongbao Feng</author>
        <description><![CDATA[BackgroundInsulin resistance and dysregulated glucose-lipid metabolism contribute to adverse outcomes in heart failure (HF), yet existing metabolic indicators have limited utility for rapid risk stratification in critically ill patients. The cholesterol, high-density lipoprotein, and glucose (CHG) index may provide a convenient metabolic risk marker in hospitalized HF patients.MethodsThis study adopted a dual-cohort retrospective design. The training cohort included 1,391 patients from the MIMIC-IV database (2008–2019), and the external validation cohort included 296 patients from an independent hospital-based cohort (July 2023 to December 2025). Patients were stratified into quartiles by CHG index. Kaplan–Meier survival analysis, Cox proportional hazards regression models, and restricted cubic spline (RCS) analysis were performed to assess the relationship between CHG index and in-hospital mortality.ResultsIn the training cohort, in-hospital mortality increased from 8.91% in Q1 to 17.87% in Q4 (log-rank test p = 0.0141). In the fully adjusted model, each 1-unit increase in CHG index was associated with a 76.8% increase in in-hospital mortality risk (HR = 1.768, 95% CI 1.337–2.338; p < 0.001). RCS analysis indicated an approximately linear positive association (P for overall < 0.001, P for nonlinearity = 0.139). The external validation cohort showed a similar association, with mortality increasing from 4.05% in Q1 to 16.22% in Q4 and a fully adjusted HR of 2.716 (95% CI 1.483–4.962, p = 0.001).ConclusionThe CHG index was independently associated with in-hospital mortality in patients with HF, with consistent findings in an external cohort. As an integrative biomarker derived from routine laboratory tests, the CHG index may reflect the interplay between metabolic dysregulation and cardiovascular vulnerability, thereby assisting early risk stratification in hospitalized patients with heart failure.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1837406</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1837406</link>
        <title><![CDATA[MIND diet moderates the associations between cerebrovascular and neurodegenerative disease burden and cognition]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Desarae A. Dempsey</author><author>Frederick W. Unverzagt</author><author>Huiping Xu</author><author>Lyndsi Moser</author><author>Sujuan Gao</author><author>Andrea Avena-Koenigsberger</author><author>Evgeny J. Chumin</author><author>Karmen K. Yoder</author><author>Puja Agarwal</author><author>Christy C. Tangney</author><author>Daniel O. Clark</author><author>Andrew J. Saykin</author><author>Shannon L. Risacher</author>
        <description><![CDATA[IntroductionThe Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet is associated with reduced dementia risk, but its role in moderating pathology–cognition relationships in high-risk populations remains unclear. This study examined associations of the MIND diet and Healthy Eating Index (HEI) with cognition and tested whether diet quality modifies the impact of brain pathology on cognitive performance.MethodsSixty-six older adults (aged 60–82 years; mean education of 12 years, 65% Black, 73% female) completed MRI and the VioScreen food frequency questionnaire (FFQ). Multivariable linear regression models examined associations between diet scores (MIND, HEI-2020) and cognitive outcomes (cognition composite, memory, executive function), adjusting for age, sex, and education level. Interaction analyses cross-sectionally tested whether diet moderated relationships between structural brain pathology–white matter hyperintensity (WMH), hippocampal, and cortical volumes–and cognition, followed by post-hoc simple slopes analyses.ResultsHigher MIND diet scores were independently associated with better memory performance (p < 0.05). These were significant interactions between WMH volume and MIND diet score across cognitive outcomes (all p-interactions < 0.05). Greater WMH volume was associated with worse cognitive performance at low (all p < 0.01), but not mean or high MIND diet scores (all p > 0.05). Similarly, cortical volume–cognition associations were present in those with low MIND diet scores and attenuated in those with mean or high scores. In contrast, the HEI-2020 score did not modify the effects of brain pathology on cognition, and neither diet quality measure modified hippocampal volume–cognition relationships.ConclusionThe MIND diet may buffer the cognitive consequences of cerebrovascular pathology and cortical atrophy in older adults at elevated dementia risk and promote cognitive resilience over general healthy eating guidelines.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1756606</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1756606</link>
        <title><![CDATA[Content and framing analysis of food supplement in the BBC news and evaluation from a nutrition science perspective]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Mustafa Bostancı</author><author>Metin Erol</author><author>Kubra Feyza Erol</author>
        <description><![CDATA[This study aims to identify the framing of dietary supplement news within the context of content analysis and to examine how these frames construct perceptions through specific contexts. For the sample, the international news organization BBC was selected. Using keyword searches on BBC’s official website, news articles were identified, and a simple random sampling method was applied to select the sample. The frames of the sampled news articles were extracted using Wordsmith software. The nutritional dimension of these frames was critically evaluated through eight analytical questions. Within this framework, which types of food supplements are most frequently featured in news content (1), Is there a scientific basis (2), is the benefit or the risk more prominent (3), how does social media shape nutritional behavior (4) and which target group does the news report address (5) The findings indicate that media content predominantly presents supplements in a benefit-oriented manner and positions them not as a complement to food but rather as an alternative thereby shaping public perception. This study seeks to provide a multidisciplinary contribution to literature at the intersection of communication and nutrition/dietary sciences. Ensuring that social and digital communication channels operate parallel with evidence-based scientific and clinical studies can enhance the accuracy, reach, and effectiveness of public guidance. Such coordinated dissemination of knowledge plays a pivotal role in directing individuals toward safe, appropriate, and scientifically informed supplement practices.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1802388</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1802388</link>
        <title><![CDATA[Adherence to the EAT-Lancet diet and the risk of heart failure in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: A prospective cohort study]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Peng Fu</author><author>Hong Zheng</author><author>Kuangyi Wu</author><author>Yulong Lan</author><author>Dan Wu</author><author>Weiqiang Wu</author><author>Huancong Zheng</author><author>Zefeng Cai</author><author>Yuxian Wang</author><author>Qiuyue Lin</author><author>Bo Zhang</author><author>Youren Chen</author>
        <description><![CDATA[Background and objectiveIn 2019, the EAT-Lancet Commission on Healthy Diets from Sustainable Food Systems proposed the EAT-Lancet planetary health diet as a universal reference dietary pattern aimed at promoting human health while minimizing environmental degradation. However, epidemiological evidence regarding the association between adherence to the EAT-Lancet diet and the risk of heart failure (HF), particularly among individuals with cardiovascular-kidney-metabolic syndrome (CKMs) stages 0–3, remains limited. Therefore, this study aimed to examine the associations between adherence to the EAT-Lancet dietary pattern, its individual dietary components, and the risk of HF among individuals at CKMs stages 0–3.Materials and methodsIn this prospective study, a total of 120,849 participants with CKMs stages 0–3 from the UK Biobank cohort were included. Dietary data were collected using an online 24-h dietary recall questionnaire. The EAT-Lancet Diet Index, ranging from 0 to 14, was constructed based on the EAT-Lancet reference diet to evaluate adherence. Cox proportional hazards models and restricted cubic spline functions were used to assess the associations between the EAT-Lancet Diet Index, its dietary components, and HF risk.ResultsOver a median follow-up of 14.88 years, 2,454 participants developed HF. A higher EAT-Lancet Diet Index was significantly associated with a lower risk of HF compared to the lowest index group (hazard ratio [HR]: 0.88; 95% confidence interval [CI]: 0.80, 0.97). This association remained robust across subgroup and multiple sensitivity analyses. Restricted cubic spline analysis revealed a significant inverse linear relationship between the EAT-Lancet Diet Index and HF risk. Among dietary components, reduced intake of red meat (beef, lamb, and pork) (HR: 0.90; 95% CI: 0.83, 0.98) and increased intake of peanuts or other nuts (HR: 0.76; 95% CI: 0.60, 0.95) were significantly associated with lower HF risk.ConclusionThis study demonstrates that greater adherence to the EAT-Lancet diet is significantly associated with a reduced relative hazard of HF among individuals with CKM stages 0–3, particularly through reduced consumption of red meat and increased intake of peanuts or other nuts.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1817773</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1817773</link>
        <title><![CDATA[In silico molecular docking and in vivo evidence of whey protein concentrate-mediated protection against thioacetamide-induced intestinal toxicity in male albino rats via modulation of oxidative stress, inflammation, apoptosis, and fibrosis]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Huda Fayez Al-Rashedi</author><author>Reem Alenazi</author><author>Nashmiah S. Alshammari</author><author>Mona A. Ibrahim</author><author>Sherif R. Mohamed</author><author>Hanan A. Okail</author>
        <description><![CDATA[Oxidative stress is a foremost cause in the etiology and progression of numerous illnesses. Thioacetamide (TA) has been demonstrated to promote oxidative stress and has been shown to be harmful in a variety of organs. The antioxidant activity of whey protein concentrate (WPC) has generated a lot of interest since it can help with the nutritional treatment of chronic disorders. The present study examined WPC’s antioxidant qualities, evaluating any potential defenses against TA-induced intestinal damage in rats. Forty rats were equally divided into four groups and treated for 5 days per week over 3 weeks: untreated control; TA (thioacetamide 100 mg/kg/day i.p.); WPC (whey protein 300 mg/kg/day oral); and WPC + TA (WPC orally followed 2 h later by TA i.p.). The results showed that TA treatment dramatically increased levels of nitric oxide and malondialdehyde while significantly decreasing levels of glutathione and activity of antioxidant enzymes (superoxide dismutase plus catalase) in intestinal tissue. Furthermore, TA injection showed higher values in apoptotic markers (Bcl-2 and Bax) and inflammatory indicators (IL-1β and TNF-α), and reduced expression of genes such as ZO-1 and HO-1 in intestinal tissue. Using a molecular docking study, the potential binding mechanisms of the antioxidant peptide with TGF-β and Keap1were examined. Additionally, there were notable immunopositive reactions for NF-kB and α. SMA, as well as significant histological changes, increased collagen fiber deposition, and duodenal goblet cell hyperplasia were observed in the TA group. However, WPC pretreatment significantly decreased intestinal tissue’s oxidative stress, pro-inflammatory, apoptotic, and fibrotic indicators, hence reducing TA-induced intestinal damage, suggesting WPC can be a useful and economical feed option that improves intestinal health.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1807070</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1807070</link>
        <title><![CDATA[Maintenance hemodialysis patients’ nutritional literacy and its relationship with frailty: a cross-sectional study based on latent profile analysis]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Jiquan Zhang</author><author>Wei Qing</author><author>Fan Xu</author>
        <description><![CDATA[BackgroundMalnutrition is a common complication among maintenance hemodialysis (MHD) patients. Although the association between nutritional literacy and frailty is well established, prior research has largely focused on individual risk factors or relied solely on total scores from nutrition-related scales, thereby overlooking heterogeneity within patient groups. As a result, the specific relationship between distinct patterns of nutritional literacy and frailty remains unclear.ObjectiveTo identify distinct nutritional literacy profiles among MHD patients, examine sociodemographic differences across these profiles, and assess their association with frailty.MethodBetween May and September 2024, we recruited a convenience sample of 335 MHD patients from the Department of Nephrology at a tertiary Grade A hospital in Deyang, Sichuan Province. Participants completed questionnaires on demographic characteristics, frailty (assessed using the Tilburg Frailty Indicator [TFI]), and nutritional literacy (measured by the Nutrition Literacy Assessment Questionnaire for Maintenance Hemodialysis Patients [NLAQ-MHD]). Latent profile analysis was used to identify distinct nutritional literacy profiles. Bivariate and multivariable logistic regression models examined associations between profile membership and sociodemographic variables. Differences in frailty across profiles were evaluated using analysis of variance.ResultsLatent profile analysis revealed three distinct nutritional literacy profiles among MHD patients: low nutritional literacy (26.9%), moderate nutritional literacy (59.4%), and high nutritional literacy (13.7%). Multivariable logistic regression showed that education level and Per capita monthly household income were significant predictors of profile membership (p < 0.05). Frailty levels differed significantly across the three nutritional literacy profiles.ConclusionThis study offers new insights into the heterogeneity of nutritional literacy among MHD patients and demonstrates that lower nutritional literacy is associated with greater frailty. These findings not only advance knowledge for future research but also provide a basis for developing targeted frailty intervention strategies in this population.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1762014</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1762014</link>
        <title><![CDATA[Case Report: Beyond the ulcer: 51-month durability of left gastric artery embolization for obesity management in an antiplatelet-dependent, surgery-ineligible patient]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Case Report</category>
        <author>Min Hu</author><author>Xiangrui Chen</author><author>Limei Zhou</author><author>Maolin Sun</author><author>Yunwei Han</author><author>Jingting Zhao</author>
        <description><![CDATA[We report a 51-month follow-up of transcatheter left gastric artery embolization (LGAE) in a 54-year-old male with central obesity (BMI 29.1 kg/m2, waist circumference 107 cm), post-stroke disability, osteoarthritis-induced immobility, compulsive binge eating, alcohol dependence, and clopidogrel-treated antiplatelet therapy—rendering conventional weight-loss interventions ineffective or contraindicated. Despite developing an 8-cm iatrogenic gastric ulcer at 30 days post-procedure, complete endoscopic healing was achieved with proton pump inhibitors and mucosal protectants. Sustained weight loss of 15.2% (from 84 kg to 71.2 kg) with 14.6 cm waist reduction correlated with resolution of knee pain (WOMAC score 68 → 12), sleep apnea, fatty liver (ALT 119 → 28 U/L), and dyslipidemia. This case demonstrates LGAE’s long-term efficacy in high-risk, surgery-ineligible obesity while highlighting the necessity of rigorous management for significant embolization-related complications, suggesting vascular remodeling capacity in gastric mucosa.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1817924</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1817924</link>
        <title><![CDATA[The role of vitamin D in the management and rehabilitation of gestational diabetes mellitus]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Opinion</category>
        <author>Ting Zhang</author><author>Qian Zhou</author><author>Lulu Shen</author><author>Song Gao</author>
        <description></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1821389</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1821389</link>
        <title><![CDATA[Combined diet and physical activity effects on health-related outcomes in people with overweight or obesity: an overview of systematic reviews]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Systematic Review</category>
        <author>Atef Salem</author><author>Achraf Ammar</author><author>Khaled Trabelsi</author><author>Omar Boukhris</author><author>Juliane Heydenreich</author><author>Hadeel Ali Ghazzawi</author><author>Adam Tawfiq Amawi</author><author>Giuseppe Grosso</author><author>Piotr Zmijewski</author><author>Haitham Jahrami</author><author>Waqar Husain</author><author>Hamdi Chtourou</author><author>Wolfgang I. Schöllhorn</author>
        <description><![CDATA[BackgroundThis overview synthesized evidence from systematic reviews (SRs) of combined physical activity (PA) and diet interventions versus diet-only or PA-only approaches on obesity-related anthropometric, cardiometabolic, and physical fitness outcomes, and identified program features linked to better effects.MethodsWe conducted an Overview of SRs following Cochrane guidance and PRIOR standards. Five databases were searched until June 13, 2024, and Google Scholar was updated on January 25, 2025. Eligible SRs synthesized randomized controlled trials of combined PA and diet interventions in people with overweight or obesity. We extracted key intervention characteristics, outcomes, and meta-analytic estimates where available. Methodological quality was assessed with AMSTAR 2, and overlap was quantified using the corrected covered area (CCA).ResultsThirty-two SRs (19 meta-analyses) met inclusion criteria. In adults, combined PA and diet interventions generally outperformed single-component comparators for reducing weight, BMI, waist circumference, and fat mass, and improving cardiorespiratory fitness. More favorable and sustained effects were most often reported in programs lasting ≥6–12 months with frequent, structured contact and supervised, resistance-inclusive exercise. In children and adolescents, face-to-face and family-engaged programs produced the most consistent improvements in BMI/BMI-z, but effects often attenuated 6–12 months after program end without maintenance. In older adults, combined programs reduce fat mass while preserving lean mass, strength, and function. Across diverse settings (including type 2 diabetes, workplaces, and digital delivery), combined interventions improved glucose control, insulin resistance, lipids, and inflammation, and some benefits occurred even without additional weight loss. Long-term lifestyle programs reduced incident type 2 diabetes by about half. Review quality varied (31% high; 69% low/critically low) and overlap between SRs was minimal (CCA 0.0–0.6%).ConclusionCombined PA and diet interventions tended to outperform diet-only and PA-only approaches. The most consistent and durable benefits were linked to longer duration, higher contact, supervision, resistance training, and family engagement in youth, underscoring maintenance planning. These findings support prioritizing structured lifestyle programs, including scalable hybrid/digital delivery models, while interpreting effects cautiously given the predominance of low-quality SRs. Future research should improve rigor, standardize outcomes, report intervention dose and behavior-change methods, include longer follow-up, and improve representation of underserved groups.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1720603</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1720603</link>
        <title><![CDATA[Nutrition-associated health levels in cancer patients based on the ICF: an expanded study of 300 cases]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Jinjin Chen</author><author>Shuqian Sun</author><author>Hua Shen</author><author>Jiangang Liu</author><author>Feng Lin</author>
        <description><![CDATA[BackgroundEarly assessment of nutrition-associated health levels in patients with cancer—encompassing functioning, activities, and participation—is increasingly recognized as essential for nutrition assessment and cancer rehabilitation. Using a combined approach of item response theory (IRT) and graph modeling, our previous study developed a 32-item two-parameter logistic model (2PLM) for assessing the nutrition-associated health levels of cancer patients. By expanding the sample size and updating the methods, this study aimed to refine and extend the previous findings.MethodsThis study collected International Classification of Functioning, Disability, and Health (ICF) data from 300 cancer patients via a maximum variation sampling strategy, including 200 newly recruited patients and 100 from our previous study. Person abilities (θ) and item parameters were calculated by constructing an IRT model, and the benefit index was estimated using a graph model.ResultsThe study constructed a 43-item three-parameter logistic model (3PLM) with high reliability (Cronbach’s α = 0.945, latent class reliability coefficient (LCRC) = 0.967). The estimated θ showed a significantly strong correlation with the Mini-Nutritional Assessment (MNA) (p < 0.001, rwinsorized = 0.73), the Patient-Generated Subjective Global Assessment (PG SGA) (p < 0.001, rwinsorized = −0.74), and the Nutrition Risk Screening 2002 (NRS 2002) (p < 0.001, rwinsorized = −0.60), indicating high validity. In the graph model, 33 items formed a maximal connected subnetwork and 30 items exhibited a significant benefit index.ConclusionThe study established a 43-item 3PLM for assessing nutrition-associated health levels in cancer patients and estimated both item parameters and the benefit index. By incorporating a larger sample size and updated analytical methods, the study extended prior findings and supports the utility of this integrated approach for nutritional assessment and cancer rehabilitation.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1843196</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1843196</link>
        <title><![CDATA[Valorization of camel milk into probiotic-fermented high-energy beverages incorporating Khalas date and nuts: nutritional quality and bioactives profiling]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Raed Alayouni</author>
        <description><![CDATA[BackgroundCamel milk offers nutritional potential for arid-region functional foods, but high-energy probiotic formulations with balanced macros and bioactives remain underdeveloped.MethodsThis study developed PFHECMs sweetened with 7.5% Khalas date (KD) and fortified with 0% (F1), 15% (F2), or 30% (F3) nut mix to create functional foods with enhanced nutritional and bioactive properties. The formulated beverages were analyzed for proximate composition, phytochemical content, antioxidant activity, color attributes, fatty acid profile, amino acid composition, and volatile compounds using standard analytical procedures.ResultsProximate analysis revealed dose-dependent improvements: protein tripled from 3.13 g100 mL−1 in F1 to 9.13 g100 mL−1 in F3, fat increased 5-fold to 14.99 g100 mL−1, dietary fiber rose to 1.99 g100 mL−1, and energy reached 233 kcal 100 mL−1. Phytochemicals surged, with total phenolics climbing from 123.25 mg GAE 100 mL−1 in F1 to 506.33 mg GAE 100 mL−1 in F3, paralleled by DPPH radical scavenging (173.14–785.29 μmol TE 100 mL−1), total flavonoids (17.27–54.29 mg QE 100 mL−1), and total flavonols (8.82–22.24 mg QE 100 mL−1), confirming strong antioxidant potential. Color became progressively creamier and more appealing, with lightness decreasing from L* 83.56 to 64.66 and yellowness, chroma, and overall color difference increasing. Fatty acid profiles improved markedly, with saturated fats declining from 65.82% in F1 to 32.04% in F3, monounsaturated fats rising to 43.83%, and polyunsaturated fats surging to 24.13% (linoleic acid 21.78%), enhancing the potential of cardiovascular health indices. Amino acid analysis showed nut addition modestly diluted essential amino acids (EAAs) from 27.30% to ≈ 25.81% of total amino acids (TAAs), with EAA: NEAA ratio falling from 0.38 to 0.35, though biological value (54.9–62.4%), essential AA index (88.9–101.3%), and age-group requirement indices remained robust (>50% for adults/schoolchildren). Functional non-essential amino acids (NEAAs), such as arginine, glycine, and cystine, increased, supporting potential metabolic benefits. Volatile GC–MS profiling identified lipid-derived aldehydes (hexanal, nonanal), acids, alcohols, lactones, and nut/date terpenes (caryophyllene, ocimene) as dominant, with F3 exhibiting complex fruity-spicy-nutty aromas versus F1’s pungent dairy notes.ConclusionThese PFHECMs demonstrate a sustainable use of camel milk by combining camel milk proteins with unsaturated fats, date-derived prebiotic fibers, and nuts to produce high-protein, antioxidant-rich beverages with improved nutritional profiles. While these compositional attributes are consistent with potential benefits for physically active individuals and populations in arid or protein-deficient regions, dedicated in vivo, sensory, and consumer studies are required to confirm practical applicability and acceptability.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1714510</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1714510</link>
        <title><![CDATA[A study on dietary diversification intervention for elderly patients with chronic heart failure who can eat by mouth]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Wenlin Zhou</author><author>Longya Si</author><author>Yumei Deng</author><author>Jing Li</author><author>Changxiu Li</author>
        <description><![CDATA[IntroductionConventional CHF nutrition counseling is often one-size-fits-all. We developed and tested a DDS-guided, tiered dietary diversification program for elderly CHF patients able to eat orally.MethodA quasi-experimental study with a non-randomized, non-concurrent control design was used. Eighty-eight elderly oral-feeding CHF patients were selected from the Cardiovascular Department of a tertiary general hospital in Zunyi City (July–October 2022): the control group (July–August, n = 44) and the intervention group (September–October, n = 44). The control group received conventional dietary guidance, while the intervention group underwent personalized intervention based on the Dietary Diversity Score (DDS9) and nutritional status, with 2-month post-discharge follow-up. The Dietary Diversity Score (DDS9) and nutritional indicators (Heart Failure-Specific Mini Nutritional Assessment [MNA-HF], Body Mass Index BMI) were compared between the groups at baseline, 1 and 2 months post-intervention.ResultsThere were no statistically significant differences in baseline data between groups (p > 0.05). After 1 month, the intervention group showed significantly higher scores in Total DDS and specific food groups (fish, fruits, etc.) compared to the control group (p < 0.05), with a large effect size for Total DDS. After 2 months, significant improvements were maintained for Total DDS (large effect size) and MNA-HF (medium effect size) (p < 0.05). The intervention group exhibited a significantly greater upward trend in dietary diversity over time (p < 0.001, large effect size). Although absolute BMI trends did not differ significantly, the increase in BMI at 2 months was significantly greater in the intervention group (medium effect size).DiscussionA DDS-guided, tiered intervention improved dietary diversity and nutritional status over 2 months in elderly CHF patients, demonstrating practicality and scalability. Limitations include the non-randomized, single-center design and short follow-up; longer multicenter trials are needed to confirm durability and clinical impact.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1836804</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1836804</link>
        <title><![CDATA[Prognostic impact of glim-defined malnutrition and phase angle in patients with digestive tumors]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>María González-Pacheco</author><author>Carlos López-Pereira</author><author>Arnau Gramage-Viñets</author><author>Almudena Lara-Barea</author><author>Rocío Fernández-Jiménez</author><author>Francisco Javier Vílchez-López</author>
        <description><![CDATA[Background/ObjectivesDisease-related malnutrition is frequent among patients with digestive neoplasms and is associated with poorer prognosis. The Global Leadership Initiative on Malnutrition (GLIM) criteria have been proposed to standardize its diagnosis; however, their prognostic value in combination with morphofunctional parameters remains insufficiently defined. This study aimed to analyze the association between GLIM-defined malnutrition, phase angle (PhA), and overall survival in patients with digestive cancer.MethodsWe conducted a retrospective longitudinal study including 131 adult patients with digestive neoplasms. Nutritional status was established according to GLIM criteria. Morphofunctional assessment consisted of bioelectrical impedance analysis with PhA determination, muscle ultrasound, and handgrip strength. Overall survival was evaluated using Kaplan–Meier curves and Cox regression models adjusted for age and sex.ResultsSignificant differences between the three GLIM categories were observed for several bioimpedance-derived parameters, including body cell mass (BCM), fat-free mass (FFM), and appendicular skeletal muscle mass (ASMM) (p < 0.001). PhA was independently associated with GLIM-defined nutritional severity (OR = 2.51; 95% CI: 1.26–4.99; p = 0.009), and a cutoff of 3.8° discriminated survival (p < 0.05). In the multivariable model, malnutrition was independently associated with higher mortality (HR = 4.35; 95% CI: 1.04–16.67; p = 0.044), while PhA showed a protective association (HR = 0.57; 95% CI: 0.34–0.97; p = 0.039).ConclusionGLIM-defined malnutrition is independently associated with overall survival in patients with digestive cancer. Phase angle provides additional prognostic information and improves risk stratification.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1828769</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1828769</link>
        <title><![CDATA[Nourish to flourish: sustainable diets, sports nutrition, and psychology in college life]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Jun Huang</author><author>Zhuozhi Qi</author>
        <description><![CDATA[BackgroundIn this paper, the author examines the intersections of sustainable diets, sports nutrition, and psychology as applied to college life. Since college students experience specific difficulties in academic achievement, physical health, and mental health, this study explores the impact of nutrition and psychological factors on their everyday lives.ObjectiveIt focuses on sustainable eating habits that not only enhance the environment and long-term health but also the effects of appropriate sports nutrition on academic achievement and physical fitness. Furthermore, the paper explores the psychological side of eating habits, such as body image, stress, and eating behaviors, and emphasizes the significance of mental state in achieving optimal nutrition.MethodsThis study combines the lenses of nutrition science, psychology, and environmental sustainability to provide actionable guidance that helps college students make informed, healthy, and sustainable dietary decisions to improve their bodies and minds.ResultsThis paper discusses how sustainable diets affect long-term health outcomes and academic and physical performance in sports nutrition. It also addresses the psychological factors that influence eating habits and their connections to mental health and body image.ConclusionThe paper highlights the significance of psychological conditions in realizing optimal nutrition and offers practical information to college students to create informed, healthy and sustainable food choices to improve physical and mental health.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1755750</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1755750</link>
        <title><![CDATA[Missed opportunities in nutritional care: prevalence, mortality, and resource utilization in internal medicine wards]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Ricardo C. Marinho</author><author>Ana Craveiro</author><author>Susana Ferreira</author><author>Elisabete Carolino</author><author>Marta S. Lopes</author><author>João A. Correia</author><author>Anibal Marinho</author><author>Marisa D. Santos</author>
        <description><![CDATA[BackgroundMalnutrition is a highly prevalent and underdiagnosed condition among hospitalized patients, especially in internal medicine wards. Hospital malnutrition is associated with increased morbidity, mortality, prolonged admissions, and a substantial economic burden.ObjectivesThis study aimed to assess the clinical and economic impact of nutritional risk in patients admitted to internal medicine wards, focusing on mortality, hospital resource utilization, and the effectiveness of nutritional interventions.MethodsA retrospective cohort study was conducted at ULS Santo António, Porto, including 1,150 hospital admissions from January to December 2022. All adult patients with nutritional risk screening (NRS-2002) in the first 48 h of admission were included. Data were collected from hospital information systems on demographic, clinical, and economic variables, with outcomes including in-hospital mortality, readmissions at 30, 90, and 180 days, and one-year post-discharge mortality.ResultsNutritional risk (NRS-2002 ≥ 3) was identified in 42.4% of patients (n = 488), while ICD-10 malnutrition coding at discharge was recorded in only 0.7% of admissions. Of patients at nutritional risk, 74.4% (n = 363) received no nutritional supplementation. Nutritional risk was associated with higher in-hospital mortality, longer length of stay, and increased costs across all resource categories. In the time-dependent Cox model, patients at nutritional risk without supplementation showed a markedly higher hazard of in-hospital death at admission (HR 23.32, 95% CI 13.09–41.56), with this excess hazard attenuating over time. Patients at nutritional risk who received supplementation also showed elevated early risk (HR 6.15, 95% CI 2.96–12.80), though lower than unsupplemented patients. A similar pattern was observed for one-year post-discharge mortality. Total hospitalization costs were approximately 79% higher in at-risk patients, driven mainly by longer length of stay.ConclusionNutritional risk affected 42.4% of internal medicine inpatients and was associated with higher mortality and resource use. The finding that 74.4% of at-risk patients received no nutritional intervention represents a substantial missed opportunity. Patients who received nutritional supplementation showed a pattern of lower mortality risk than unsupplemented at-risk patients, consistent with but not proving a beneficial association. These findings support systematic nutritional screening and timely intervention in hospital care.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1849386</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1849386</link>
        <title><![CDATA[Ginsenoside Rb1 alleviates overtraining-induced oxidative stress in mouse liver by stimulating mitophagy via Nrf2 pathway]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Jianing Lu</author><author>Ruotian Xu</author><author>Yuexuan Gao</author><author>Luye Zong</author><author>Daming Wang</author><author>Jing Li</author>
        <description><![CDATA[IntroductionModerate exercise induces beneficial adaptive responses in the body, whereas sustained high-intensity exercise without adequate recovery leads to overtraining syndrome (OTS), a pathological condition associated with multiple organ damage, especially liver injury. Currently, safe and effective nutritional interventions for OTS-induced liver injury remain limited. This study aimed to investigate the protective effect of ginsenoside Rb1 (Gs-Rb1), the primary bioactive component of ginseng, against OTS-induced liver injury and to elucidate its underlying molecular mechanism.MethodsWe established an overtraining (OT) mouse model using ICR mice, and evaluated the hepatoprotective effect of Gs-Rb1 using histopathological observation, biochemical analysis, immunofluorescence staining, Western blot, and other related techniques. The core regulatory mechanism was verified using chloroquine (CQ, an autophagy inhibitor) and ML385 (a specific Nrf2 inhibitor).ResultsOT intervention induced significant oxidative stress and liver injury in mouse liver, whereas Gs-Rb1 administration effectively alleviated liver damage, improved exercise performance, and mitigated OT-induced oxidative stress and mitochondrial impairment in the liver by activating mitophagy. Mechanistically, Gs-Rb1 promoted the nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2), and further activated the downstream PTEN-induced kinase 1 (PINK1)/Parkin RBR E3 ubiquitin protein ligase (Parkin) pathway to drive mitophagy. Inhibitor validation experiments further confirmed that the hepatoprotective effect of Gs-Rb1 was autophagy-dependent, and Nrf2 was a key regulator of Gs-Rb1-mediated mitophagy.DiscussionThis study demonstrates that Gs-Rb1 ameliorates OT-induced oxidative stress in mouse liver via Nrf2-dependent mitophagy. Our findings indicate that targeting mitophagy via the Nrf2 pathway represents a promising nutritional strategy to alleviate overtraining-related liver injury, providing a theoretical basis for the application of natural bioactive compounds such as Gs-Rb1 in the field of sports nutrition and health promotion.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1785886</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1785886</link>
        <title><![CDATA[Vitamin D levels and prolonged menstrual cycle in women with polycystic ovary syndrome: a cross-sectional study]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Lijing Wang</author>
        <description><![CDATA[ObjectiveThis study evaluated serum vitamin D (VD) levels in women with polycystic ovary syndrome (PCOS) and assessed their association with menstrual cycle characteristics.MethodsIn this cross-sectional study, 449 women diagnosed with PCOS were stratified based on 25-hydroxyvitamin D [25(OH)D] levels: low VD group (<20 ng/mL) and normal VD group (≥20 ng/mL). Menstrual cycles of 26–35 days were defined as normal; cycles exceeding 35 days were classified as prolonged. All participants underwent measurements of body mass index (BMI), fasting plasma glucose (FPG), fasting insulin (FINS), and sex hormones.ResultsThe prevalence of prolonged menstrual cycles was significantly higher in the low VD group (87.2%) compared to the normal VD group (70%) (p < 0.001). Regression analysis demonstrated an inverse association between VD levels and the risk of prolonged cycles (p < 0.001). This association remained significant after adjusting for age, BMI, HOMA-IR, and total testosterone. Each 1 ng/mL increase in VD was associated with an 9% reduction in the risk of prolonged cycles. Fitted curves indicated a non-linear relationship between VD levels and the prevalence of prolonged cycles. Inflection point analysis identified VD = 27.76 ng/mL (approximately 28 ng/mL) as the inflection point. Below this level, the prevalence of prolonged cycles decreased as VD increased; above 28 ng/mL, the prevalence plateaued.ConclusionIn this cross-sectional study, lower vitamin D levels were associated with a higher prevalence of prolonged menstrual cycles among women with PCOS. This association suggests that further investigation into whether maintaining vitamin D levels at or above 28 ng/mL could influence menstrual cycle regularity in this population is warranted.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1819662</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1819662</link>
        <title><![CDATA[Analysis of the association between water iodine concentration and TyG-BMI index with thyroid diseases: a cross-sectional study in Shandong province, China]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Chun-Hu Li</author><author>Meng Zhao</author><author>Tong Zhao</author><author>Yu-Hang Liu</author><author>Zong-Yu Yue</author><author>Zhe-Xu Zhang</author><author>Xiang-Kun Zeng</author><author>Dian-Jun Sun</author><author>Peng Liu</author>
        <description><![CDATA[BackgroundWater iodine (WI) is a key factor influencing human thyroid function, and the TyG-BMI index, as a new metabolic indicator, can more comprehensively reflect an individual’s metabolic status. This study aims to investigate the correlation between two potential influencing factors with thyroid diseases.MethodsTo explore the associations between WI and TyG-BMI index with thyroid diseases, binary logistic regression analysis, interaction and mediation analyses were adopted to analyze linear associations. Restricted cubic spline regression was used to analyze nonlinear associations. Receiver Operating Characteristic curves and the Area Under the Curve (AUC) were utilized to evaluate the predictive accuracy of WI and TyG-BMI index for thyroid diseases.ResultsIn this study, among the 1,301 participants, the prevalence of thyroid diseases was significantly higher in females than in males. After adjusting for covariates, excessive WI, compared to adequate levels, was associated with higher odds of thyroiditis (OR = 1.76, 95% CI = 1.01–3.08), thyroid nodules (OR = 1.73, 95% CI = 1.16–2.58), hypothyroidism (OR = 1.94, 95% CI = 1.06–3.54), and multiple thyroid diseases (OR = 2.66, 95% CI = 1.50–4.71). Besides, TyG-BMI index in the fourth quartile (Q4) was also identified as a risk factor for thyroiditis (OR = 2.06, 95% CI = 1.13–3.76). Nonlinear analyses showed that WI and TyG-BMI had significant nonlinear correlation with thyroid nodules (p = 0.028; p = 0.042).ConclusionThis study identified significant associations between WI and TyG-BMI with the prevalence of thyroid diseases. Therefore, for the prevention and control of thyroid diseases, it should be taken that targeted comprehensive measures from environmental (WI) and individual (TyG-BMI) perspectives.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1815305</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1815305</link>
        <title><![CDATA[Effect of kombucha soymilk on high fat diet mice: integrated insights from gut microbiome and metabolome analyses]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Yingyi Liu</author><author>Min Li</author><author>Mingkun Pan</author>
        <description><![CDATA[IntroductionKombucha, soymilk, and tea-derived bioactive compounds have individually been associated with metabolic benefits, while the effects of kombucha soymilk on diet-induced hyperlipidemia and its associated gut microbiome–metabolome changes remain unclear.MethodsIn this study, we established a high-fat diet (HFD)-induced obese mouse model and administered kombucha soymilk as a dietary intervention. We systematically investigated the effects on body weight gain, lipid levels, and hepatic antioxidant capacity, and further explored the associated changes in gut microbiota composition and key metabolites underlying its lipid-lowering effects.Results and discussionBiochemical and histological analyses revealed that kombucha soymilk consumption significantly attenuated body weight gain in mice (p< 0.05), reduced serum and hepatic triglyceride (TG) and total cholesterol (TC) levels (p < 0.01), enhanced hepatic antioxidant capacity, and ameliorated hepatic steatosis. Microbiome analysis revealed that kombucha soymilk consumption altered the gut microbial community structure in mice, increasing the relative abundances of Enterococcus, Bifidobacterium, and Turicibacter. Untargeted metabolomics further suggested altered enrichment of pathways related to pyruvate metabolism, linoleic acid metabolism, bile secretion, and cAMP signaling. In conclusion, kombucha-fermented soymilk improved hyperlipidemia-related phenotypes in HFD-fed mice and was associated with selective gut microbial and metabolic alterations. These findings support its potential as a functional dietary intervention, although the mechanistic interpretation remains exploratory and requires further validation.]]></description>
      </item><item>
        <guid isPermaLink="true">https://www.frontiersin.org/articles/10.3389/fnut.2026.1826047</guid>
        <link>https://www.frontiersin.org/articles/10.3389/fnut.2026.1826047</link>
        <title><![CDATA[Dose–response relationships between early postoperative nutrition and subsequent complications in gastrointestinal cancer: optimal intake ranges for energy and protein]]></title>
        <pubdate>2026-05-13T00:00:00Z</pubdate>
        <category>Original Research</category>
        <author>Ziqi Liu</author><author>Yuntao Hao</author><author>Jialin Li</author><author>Min Zhao</author><author>Ji Zhang</author><author>Qian Lu</author><author>Yanfei Wang</author><author>Yanli Wang</author><author>Liqing Gong</author><author>Qi Yu</author><author>Zhaode Bu</author><author>Zhi Peng</author><author>Xiaojiang Wu</author><author>Yu Fang</author>
        <description><![CDATA[Background and aimPostoperative complications remain common after major gastrointestinal (GI) cancer surgery. Although early nutritional support is a core component of enhanced recovery protocols, optimal postoperative targets for energy and protein intake remain uncertain. This study aimed to characterize dose–response relationships between early postoperative nutritional intake and postoperative complications.MethodsThis prospective observational cohort included adults undergoing elective gastrectomy or partial colectomy for GI malignancy. Postoperative energy and protein intake were quantified during postoperative days 1-2 (POD 1-2). Overall postoperative complications occurring after POD 2 and within 30 days after surgery were the primary outcome; infectious complications were secondary. Nonlinear associations were examined using multivariable logistic regression with restricted cubic splines (RCS) as the primary method, supported by generalized additive and quadratic models. Analyses were adjusted for demographic, surgical, oncologic, and nutritional covariates, including GLIM-defined malnutrition. Optimal intake ranges were defined using a CI-overlap criterion with bootstrap validation.ResultsAmong 642 patients, early postoperative energy intake demonstrated a statistically significant nonlinear association with complication risk (p-for nonlinearity = 0.018). The nadir occurred at 14.4 kcal/kg/day, with an optimal intake range of 12.8–20.1 kcal/kg/day. Protein intake showed a less consistent association, without statistically significant evidence of nonlinearity (p = 0.166). The nadir occurred at 0.81 g/kg/day, with an optimal intake range of 0.55–1.51 g/kg/day, with no consistent upper harm threshold observed within routine clinical ranges.ConclusionEarly postoperative energy intake after GI cancer surgery demonstrated a robust nonlinear association with postoperative complications, with lowest predicted risk observed at moderate caloric provision. In contrast, protein intake showed a less consistent association and a wider estimated optimal range. These findings warrant further investigation of individualized, precision-oriented postoperative nutrition strategies in surgical oncology.]]></description>
      </item>
      </channel>
    </rss>