AUTHOR=Vetro Calogero , Romano Alessandra , Ancora Flavia , Coppolino Francesco , Brundo Maria V. , Raccuia Salvatore A. , Puglisi Fabrizio , Tibullo Daniele , La Cava Piera , Giallongo Cesarina , Parrinello Nunziatina L. 

TITLE=Clinical Impact of the Immunome in Lymphoid Malignancies: The Role of Myeloid-Derived Suppressor Cells

JOURNAL=Frontiers in Oncology

VOLUME=Volume 5 - 2015

YEAR=2015

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2015.00104

DOI=10.3389/fonc.2015.00104

ISSN=2234-943X

ABSTRACT=The better definition of the mutual sustainment between neoplastic cells and immune system has been translated from the bench to the bedside acquiring value as prognostic factor. Additionally, it represents a promising tool for improving therapeutic strategies. In this context, myeloid-derived suppressor cells have gained a central role in tumor developing with consequent therapeutic implications. In this review, we will focus on the biological and clinical impact of the study of myeloid-derived suppressor cells in the settings of lymphoid malignancies.