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CORRECTION article

Front. Oncol., 24 September 2020
Sec. Neuro-Oncology and Neurosurgical Oncology
This article is part of the Research Topic Meningioma: From Basic Research to Clinical Translational Study View all 40 articles

Corrigendum: An Overview of Managements in Meningiomas

Lianhua Zhao Lianhua Zhao 1Wei Zhao Wei Zhao 1Yanwei Hou Yanwei Hou 2Cuixia Wen Cuixia Wen 3Jing Wang Jing Wang 4Pei Wu Pei Wu 5Zaiyu Guo Zaiyu Guo 2
  • 1 Department of Neurology, Tianjin TEDA Hospital, China
  • 2 Department of Neurosurgery, Tianjin TEDA Hospital, China
  • 3 Department of Radiotherapy, Xuzhou Central Hospital, China
  • 4 Department of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, China
  • 5 Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, China

A Corrigendum on
An Overview of Managements in Meningiomas

by Zhao, L., Zhao, W., Hou, Y., Wen, C., Wang, J., Wu, P., et al. (2020). Front. Oncol. 10:1523. doi: 10.3389/fonc.2020.01523

In the original article, there were mistakes in the order of Figure 1 and Figure 2 as published. The positions of the two figures were reversed. The corrected Figure 1 and Figure 2 appear below.

FIGURE 1
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Figure 1. Current treatment strategies for meningioma. For small and asymptomatic meningiomas, an strategy of “wait and see” is recommended, clinical and MRI evaluation was performed every 6 months after an initial observation. If patients do remain asymptomatic, annually after 5 years. If the patient's life expectancy is short, follow-up may not be necessary. Symptomatic meningioma should be removed to the maximum extent. Patients who are unwilling to undergo surgery, the elderly or obviously disabled can choose SRT/SRS or chemotherapy. Patients with WHO grade I meningioma were followed up after GTR, and SRT/SRS was recommended after STR. For WHO grade II meningioma, intimate follow-up is recommended after GTR, while SRT/SRS is recommended after STR. For WHO grade III meningiomas, adjuvant radiotherapy are recommended regardless of the grade of resection. Adapted from Goldbrunner et al. (6). EANO guidelines for the diagnosis and treatment of meningiomas. WHO, world health organization; GTR, gross total resection; STR, subtotal resection; SRT, stereotactic radiotherapy; SRS, stereotactic radiosurgery.

FIGURE 2
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Figure 2. The overexpression of RTK can activate important mitogenic pathways, including Ras, MAPK, PI3K-Akt, Mtor, and other intracellular signals, which can promote the proliferation of tumor cells. However, PDGFR/EGFR/VEGFR inhibitors can inhibit the activation of RTK, thus reverse this process and lead to tumor cell apoptosis. Chemotherapy drugs such as hydroxyureae and temozolomide can act on cell nucleus, inhibit tumor cells proliferation by inducing cell apoptosis. PDGFR, platelet-derived growth factor receptor; EGFR, epidermal growth factor receptor; VEGFR, vascular endothelial growth factor receptor; RTK, receptor tyrosinekinase; Ras, PI3K, phosphatidylinositol 3-kinase; MAPK, mitogen activated protein kinase; Akt, protein kinase B; mTORC, mammalian target of rapamycin C.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: meningioma, surgery, radiotherapy, stereotactic radiosurgery, target therapy

Citation: Zhao L, Zhao W, Hou Y, Wen C, Wang J, Wu P and Guo Z (2020) Corrigendum: An Overview of Managements in Meningiomas. Front. Oncol. 10:599431. doi: 10.3389/fonc.2020.599431

Received: 27 August 2020; Accepted: 01 September 2020;
Published: 24 September 2020.

Approved by:

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Copyright © 2020 Zhao, Zhao, Hou, Wen, Wang, Wu and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Pei Wu, wupei@hrbmu.edu.cn; Zaiyu Guo, guozai_yu@163.com

These authors share first authorship

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