AUTHOR=Zhang Wenzhi , Yang Gaoyi , Zhang Xu , Ni Tu 

TITLE=The Role of Contrast-Enhanced Ultrasound in Differentiating Splenic Tuberculosis From Splenic Lymphoma

JOURNAL=Frontiers in Oncology

VOLUME=Volume 12 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.891815

DOI=10.3389/fonc.2022.891815

ISSN=2234-943X

ABSTRACT=Aim:To summarize the features of splenic tuberculosis and splenic lymphoma by contrast enhanced ultrasound (CEUS), and discuss the application value of CEUS in differentiating splenic tuberculosis and splenic lymphoma.
Methods: The ultrasound and CEUS manifestations of patients with 30 splenic tuberculosis and 19 splenic lymphoma diagnosed by pathology were retrospectively analyzed, and the number of lesions, degree of splenomegaly, internal echo, color blood flow signal and CEUS manifestations of the two diseases were statistically analyzed.
Results:There was a difference in the internal echo between splenic tuberculosis and splenic lymphoma lesions, especially the strip-shaped hyperecho in the lesions, which was statistically significant P< 0.05. The ultrasound features of perisplenic, retroperitoneal and superficial lymph node enlargement were overlapping, which was statistically significant P< 0.05. The two diseases were statistically significant in age,P<0.05. Spleen tuberculosis mostly showed no enhancement and uneven enhancement, lymphoma mostly showed low enhancement and high enhancement, and CEUS showed statistically significant p< 0.05.
Conclusion:CEUS can show the microcirculation inside the lesion, judge the physical properties inside the lesion, and show the lymphoma lesions within the spleen that cannot be shown by routine ultrasound, which has important diagnostic value in differentiating splenic tuberculosis from splenic lymphoma.