AUTHOR=Ma Jing-Jing , Meng Shan , Dang Sha-Jie , Wang Jia-Zhong , Yuan Quan , Yang Qi , Song Can-Xu 

TITLE=Evaluation of a new method of calculating breast tumor volume based on automated breast ultrasound

JOURNAL=Frontiers in Oncology

VOLUME=Volume 12 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.895575

DOI=10.3389/fonc.2022.895575

ISSN=2234-943X

ABSTRACT=Objective: To evaluate the effectiveness and advantages of a new method for calculating breast tumor volume based on an automated breast ultrasound system (ABUS).
Methods: A total of 42 patients (18–70 years old) with breast lesions were selected for this study. The Ivenia ABUS 2.0 (General Electric Company, USA) was used, with a probe frequency of 6–15 MHz. Adobe Photoshop CS6 software was used to calculate the pixel ratio of each ABUS image, and to draw an outline of the tumor cross-section. The resulting area (in pixels) was multiplied by the pixel ratio to yield the area of the tumor cross-section. The Wilcoxon signed rank test and Bland-Altman plot were used to compare mean differences and mean values, respectively, between the two methods.
Results: There was no significant difference between the tumor volumes calculated by pixel method as compared to the traditional method (P＞0.05). Repeated measurements of the same tumor volume were more consistent with the pixel method. 
Conclusion: The new pixel method is feasible for measuring breast tumor volume and has good validity and measurement stability.