AUTHOR=Li Xiaoliang , Hu Lanyue , Tan Chengning , Wang Xiaojie , Ran Qian , Chen Li , Li Zhongjun TITLE=Platelet-promoting drug delivery efficiency for inhibition of tumor growth, metastasis, and recurrence JOURNAL=Frontiers in Oncology VOLUME=Volume 12 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.983874 DOI=10.3389/fonc.2022.983874 ISSN=2234-943X ABSTRACT=Nanomedicines are considered as a strategy for anticancer therapy, however, the low targeting efficiency in vivo is a great obstacle for their clinical application. Camouflaging nanomedicines with platelet membrane (PM) or platelet would significantly prolong the retention time in bloodstream, enhance the targeting ability to tumor cells and reduce the off-target on the major orangs due to the natural properties of platelet in the vivo application. In the current review, the advances of PM or platelet as smart carriers to deliver nanomedicines for the inhibition of tumor growth, metastasis and recurrence were summarized. And the opportunities and challenges of this camouflaging strategy for anticancer treatment were also discussed