AUTHOR=Yuan Lifang , Liu Jiannan , Bao Lei , Qu Huajun , Xiang Jinyu , Sun Ping 

TITLE=Upregulation of the ferroptosis-related STEAP3 gene is a specific predictor of poor triple-negative breast cancer patient outcomes

JOURNAL=Frontiers in Oncology

VOLUME=Volume 13 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1032364

DOI=10.3389/fonc.2023.1032364

ISSN=2234-943X

ABSTRACT=This study was designed to assess ferroptosis regulator gene (FRG) expression patterns in patients with triple-negative breast cancer (TNBC) based on data derived from The Cancer Genome Atlas (TCGA). Further, it was utilized to establish a TNBC FRG signature, after which the association between this signature and the tumor immune microenvironment (TIME) composition was assessed, and relevant prognostic factors were explored.