AUTHOR=Cao Yu , He Mingze , Chen Kuo , Liu Zheng , Khlusov Denis I. , Khorobrykh Tatyana V. , Cao Xinren , Panova Polina D. , Efetov Sergey K. , Kazaryan Airazat M. 

TITLE=Short- and long-term outcomes after surgical treatment of 5918 patients with splenic flexure colon cancer by extended right colectomy, segmental colectomy and left colectomy: a systematic review and meta-analysis

JOURNAL=Frontiers in Oncology

VOLUME=Volume 14 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1244693

DOI=10.3389/fonc.2024.1244693

ISSN=2234-943X

ABSTRACT=Background: Colorectal cancer is amongone of the most common cancers in the world, and splenic flexure colon cancer accounts for about 2-5% of them. There is still no consensus on the surgical treatment of splenic flexure colon cancer (SFCC), and the extent of surgical resection and lymph node dissection for splenic flexure colon cancerSFCC is still controversial.Aim: To compare the postoperative and long-term oncologic outcomes of extended right colectomy (ERC), segmental colectomy (SC) and left colectomy (LC) for splenic flexure colon cancer (SFCC) Method: Up to January 2023, retrospective and prospective studies of ERC, SC, and LC for SFCC were searched through databases. Pooled weighted/standardized mean difference (WMD/SMD), odds ratio (OR) and hazard ratio (HR) with 95% confidence interval (CI) were calculated using a fixed effects model or random effects model, and meta-analysis was performed using Stata.