AUTHOR=Kimpe Eva , Parmentier Riet , Busschaert Sara-Lise , De Mey Johan , Barbé Kurt , De Ridder Mark , Putman Koen TITLE=Quantifying societal burden of radiation-induced small bowel toxicity in patients with rectal cancer JOURNAL=Frontiers in Oncology VOLUME=Volume 14 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1340081 DOI=10.3389/fonc.2024.1340081 ISSN=2234-943X ABSTRACT=In the era of rapid succession of innovations in oncology care, the focus has shifted to selecting treatments that provide the best long-term quality of life for patients at a reasonable societal cost. Research demonstrated that the cost of capital investment is the main barrier to the broad implementation of advanced radiotherapy techniques. Our analyses demonstrated the large potential long-term cost-saving and improved quality of life of more advanced radiotherapy techniques. Such cost-effectiveness analyses have become an integral component of health technology assessments and therefore have an impact on reimbursement decisions and investments in novel cancer treatments. Hence, a more complete inclusion of benefits and costs in cost-effectiveness analyses is crucial to assess innovation in cancer care.