AUTHOR=Chen Shicheng , He Zhongcong , Meng Mi , Tian Zhong , Zhu Cheng , Fu Ni , Yu Bo 

TITLE=Case report: Sarcomatoid renal cell carcinoma masquerading as hydronephrosis

JOURNAL=Frontiers in Oncology

VOLUME=14

YEAR=2024

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1361250

DOI=10.3389/fonc.2024.1361250

ISSN=2234-943X

ABSTRACT=<p>Sarcomatoid renal cell carcinoma (SRCC), a manifestation of sarcomatoid dedifferentiation in renal cell carcinoma, is characterized by elevated invasiveness and a grim prognosis. Typically, SRCC patients present with advanced or metastatic conditions and survival rates rarely extend beyond one year. In this study, we describe a case of SRCC characterized by the patient exhibiting right flank pain without hematuria. Initially, imaging interpretations led to a diagnosis of severe hydronephrosis. Subsequently, an open right nephrectomy post-surgery confirmed the pathology of sarcomatoid renal cell carcinoma.</p>