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PERSPECTIVE article

Front. Oncol.
Sec. Gastrointestinal Cancers: Colorectal Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1394046
This article is part of the Research Topic Disparities in Early Onset Colorectal Cancer View all 6 articles

Advancing Early Onset Colorectal Cancer Research: Research Advocacy, Health Disparities, and Scientific Imperatives"

Provisionally accepted
Andrea J. Dwyer Andrea J. Dwyer 1*Aniruddha Rathod Aniruddha Rathod 2Carli King Carli King 3F.E.R. Vuik F.E.R. Vuik 4Phoung Gallagher Phoung Gallagher 3Anjee Davis Anjee Davis 3Jose Perea Jose Perea 5
  • 1 University of Colorado, Denver, United States
  • 2 University of Texas Southwestern Medical Center, Dallas, Texas, United States
  • 3 Fight Colorectal Cancer, Springfield, Missouri, United States
  • 4 Erasmus Medical Center, Rotterdam, Netherlands
  • 5 Institute of Biomedical Research, University of Salamanca, Salamanca, Spain

The final, formatted version of the article will be published soon.

    Early onset colorectal cancer (EOCRC) emerged as the fourth foremost contributor to cancer-related mortality among both genders in the late 1990s. Presently, EOCRC (<50) ranks as the leading cause of cancer mortality in men and the second leading cause in women within the United States 1 . Similar trends are now also evident globally, particularly in developed countries 2 . Furthermore, there is strong evidence confirming that health disparities persist in the diagnosis and treatment of EOCRC, with signs indicating that these gaps may worsen in specific cases 3 . These alarming trends highlight the critical need for research to inform evidence-based interventions to reduce the burden of EOCRC globally.Fight Colorectal Cancer (Fight CRC) is the leading patient advocacy group in the United States providing information on colon and rectal cancer research, prevention, treatment, and policy. It is the opinion of Fight CRC that an international, coordinated effort with the medical, research, scientific, advocacy, industry and funding community is needed to advance impactful research. Fight CRC, in partnership with José Perea, MD, PhD, of the Institute of Biomedical Research of Salamanca (IBSAL) in Spain, and partners, are working together to address this global phenomenon and are presenting a multi-faceted research approach to move the field forward.

    Keywords: early age onset colorectal cancer, EAO, EO, young colorectal cancer, colorectal cancer, research early onset colorectal cancer

    Received: 29 Feb 2024; Accepted: 27 May 2024.

    Copyright: © 2024 Dwyer, Rathod, King, Vuik, Gallagher, Davis and Perea. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Andrea J. Dwyer, University of Colorado, Denver, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.