AUTHOR=Mahtani Reshma , Harpalani Natasha , Yan Fengting , Phiel Kristen , Kovalenko Iuliia TITLE=Expanding treatment options for patients with HER2+ metastatic breast cancer with margetuximab plus chemotherapy: a case report series JOURNAL=Frontiers in Oncology VOLUME=Volume 14 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1419246 DOI=10.3389/fonc.2024.1419246 ISSN=2234-943X ABSTRACT=HER2+ breast cancer (BC) accounts for approximately 14% of total BC cases in the United States; it is highly aggressive, has a high associated risk for mortality, and a poor prognosis. These case reports demonstrate that margetuximab plus chemotherapy is a valid option for patients with HER2+ metastatic (M) BC who have received multiple HER2-targeted agents. Frontiers in Oncology is the great fit for these reports as it provides information in the setting of HER2+ MBC in which more treatment options are needed for patients.