AUTHOR=Li Jie , Tang Hong-Tao , Liu Qing , Li Cai-Han , Chen Wei-Yang , Yu Zeng-Wei , Wang Lei , Lin Lin , Zhao Jin-Lan , Zhao Chun-Yan , Chen Long-Qi , Tian Dong 

TITLE=Case report: A case of giant malignant solitary fibrous tumor of the pleura with Doege-Potter’s syndrome and review of the literature

JOURNAL=Frontiers in Oncology

VOLUME=Volume 14 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1437535

DOI=10.3389/fonc.2024.1437535

ISSN=2234-943X

ABSTRACT=The solitary fibrous tumor of the pleura (SFTP) is a rare intrathoracic neoplasm that commonly originates from the subpleural mesenchymal cells of the visceral pleura and accounts for less than 5% of all pleural tumors. We reported a case of a 54-year-old man with a two-week history of hypoglycemia, a six-month history of productive cough and fatigue, and chronic right chest pain. Radiological techniques revealed a giant intra-thoracic mass with hypervascularization, and pathological staining was carried out to make a definitive diagnosis of SFTP. Interventional embolization was conducted to block the main feeding vessels before the surgery, and an anterolateral thoracotomy combined with a transverse sternotomy was performed to achieve a complete resection, which demonstrates significant potential for further application in patients with unilateral giant SFTP. The postoperative course was uneventful, with no signs of hypoglycemia observed during the follow-up. Additionally, we reviewed and prospected the research progress on SFTP. The aim of this study is to enhance clinicians’ understanding of SFTP through our case and to provide a detailed review of the current research.