AUTHOR=Bao Jing , Sun Rui , Pan Zhenjiang , Wei Shepeng 

TITLE=Current chemotherapy strategies for adults with IDH-wildtype glioblastoma

JOURNAL=Frontiers in Oncology

VOLUME=Volume 14 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1438905

DOI=10.3389/fonc.2024.1438905

ISSN=2234-943X

ABSTRACT=Introduction: Glioblastoma, despite advancements in molecular evolution, remains incurable and has low survival rates. Currently, two of the most commonly used chemotherapy regimens are temozolomide and CCNU. This review aims to provide a comprehensive analysis of the current status of chemotherapy strategies for GBM.We reviewed the published literature describing the chemotherapy regimen differences in system treatment of GBM reported temozolomide, but there are no better alternatives. Clinical trial participation is encouraged.