AUTHOR=Amrane Karim , Le Meur Coline , Alemany Pierre , Niel Clémence , Renault David , Peillon Inès , Tissot Valentin , Abgral Ronan TITLE=Case report: Thoracic schwannoma as a diagnostic pitfall in both 18F-Choline PET/CT and 18F-FDG PET/CT JOURNAL=Frontiers in Oncology VOLUME=Volume 14 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1467344 DOI=10.3389/fonc.2024.1467344 ISSN=2234-943X ABSTRACT=We report increased 18F-FDG uptake in the right posterior mediastinal region in a 70-year-old woman following the discovery of a mass in the aftermath of a bronchitis episode. We also report increased 18F-Choline uptake in the right posterior mediastinal region in a 66-year-old man with newly discovered prostate cancer, which may indicate the presence of mediastinal metastases. Both patients had a thoracic MRI showing an intense gadolinium enhancement in the same region, consistent with thoracic schwannomas, which were subsequently proven histologically. This case highlights that schwannoma is a diagnostic pitfall in both 18F-FDG and 18F-Choline PET/CT.