AUTHOR=Ruan Liqin , Wu Xiaoyong , Peng Guiping , Zhang Jing , Chen Weili TITLE=Application of contrast-enhanced ultrasonography for gallbladder squamous cell carcinoma: a case report JOURNAL=Frontiers in Oncology VOLUME=Volume 14 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2024.1502226 DOI=10.3389/fonc.2024.1502226 ISSN=2234-943X ABSTRACT=Preoperative diagnosis of Gallbladder squamous cell carcinoma (GBSCC) is difficult, and the contrast-enhanced ultrasound (CEUS) pattern has never been reported before. We present a case of GBSCC where CEUS revealed special findings that facilitated early diagnosis. CEUS demonstrated irregular peripheral ring-like enhancement during the arterial phase, with hypoenhancement in the late phases, and an irregular non-enhancing area persistently present in the center of the lesion.