AUTHOR=Tan Tian , Huang Yuerong , Yan Rongxin , Liu Ying 

TITLE=Case Report: Peritoneal and small bowel metastasis from lung adenocarcinoma with EGFR L858R mutation

JOURNAL=Frontiers in Oncology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1423520

DOI=10.3389/fonc.2025.1423520

ISSN=2234-943X

ABSTRACT=Recently, cases of lung cancer metastasizing to atypical sites, such as the small intestine and colon, have been reported; however, peritoneal metastasis remains uncommon. Herein, we present the case of a patient with stage IV lung adenocarcinoma with an EGFR L858R mutation, who developed peritoneal metastasis involving the small intestine, leading to intestinal obstruction and death following osimertinib resistance.