AUTHOR=Li Tingting , Jiang Wei , Wang Hongjing 

TITLE=Fertility-sparing surgery in primary peritoneal serous borderline tumor: a case report

JOURNAL=Frontiers in Oncology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1480730

DOI=10.3389/fonc.2025.1480730

ISSN=2234-943X

ABSTRACT=Primary peritoneal serous borderline tumor (PPSBT) is a rare, low-malignant-potential neoplasm arising from the peritoneum, diagnosed only after excluding ovarian involvement. While typically discovered incidentally during surgery, it often presents with infertility or abdominal pain in young women. Due to its favorable prognosis and the desire to preserve fertility, fertility-sparing surgery (FSS) is a critical consideration. We report a case of PPSBT in a reproductive-aged woman who underwent three FSS procedures, demonstrating the feasibility of this approach. Our findings support FSS as a viable option for PPSBT patients after thorough exclusion of ovarian malignancy. This case underscores the importance of comprehensive surgical staging and multidisciplinary evaluation to optimize oncological and reproductive outcomes. Further research is needed to standardize management strategies for this rare condition.