AUTHOR=Lo Piccolo Roberto , Cianci Maria Chiara , Sardi Iacopo , Di Nicola Marco , Buccoliero Anna M. , Caporalini Chiara , Morabito Antonino 

TITLE=Paediatric extra-axial myxopapillary ependymoma: what to expect? Case report and literature review

JOURNAL=Frontiers in Oncology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1519842

DOI=10.3389/fonc.2025.1519842

ISSN=2234-943X

ABSTRACT=Extra-axial ependymomas are rare tumours, and myxopapillary ependymoma (MPE) is the most common subtype in children, often misdiagnosed as other sacral lesions. MPEs are considered low-grade tumours, but relapse with distant metastasis is frequent. Therefore, therefore a proper diagnosis and subsequent follow-up are warranted. The current report presents a case of extra-axial MPE in a paediatric patient who presented with an indolent sacral mass and underwent surgical resection, along with a review of the literature. The aim was to highlight the importance of diagnostic suspicion in differential diagnosis of sacral soft-tissue masses