AUTHOR=Ka Sha Mu Jie , Huang Ling , Xiong Chen yi , Zhao Chun yuan 

TITLE=Resuscitation of a case of cardiac arrest complicated by resection of a giant mediastinal tumor: a case report and literature review

JOURNAL=Frontiers in Oncology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1545496

DOI=10.3389/fonc.2025.1545496

ISSN=2234-943X

ABSTRACT=This case report describes the successful resuscitation of a 54-year-old female who experienced cardiac arrest following resection of a giant mediastinal tumor (GMT). The patient’s hemodynamic collapse was attributed to mediastinal mass syndrome, mediastinal swing, and acute re-expansion pulmonary edema. This report highlights the challenges of perioperative management in GMTs, emphasizing the importance of multidisciplinary preoperative planning, continuous hemodynamic monitoring, and prompt intervention during complications. Early recognition of hemodynamic instability, coupled with adherence to advanced resuscitation protocols, is critical for improving survival in high-risk mediastinal tumor surgeries.