AUTHOR=Jiang Shu-min , Huang Lu , Jiang Quan 

TITLE=A case report of a rare intrahepatic cholangiocarcinoma with rectal metastasis

JOURNAL=Frontiers in Oncology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1548570

DOI=10.3389/fonc.2025.1548570

ISSN=2234-943X

ABSTRACT=Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer with insidious onset, rapid progression, and poor prognosis. The lymphatic system is the main route of ICC distant metastasis, with lungs, adrenal glands, and brain as the most common extrahepatic sites. However, extrahepatic metastases of ICC have rarely been reported in patients with rectal symptoms as initial symptoms, and the diagnosis relies on the specific immunohistochemical features of intestinal lesion biopsy. Herein, this study presents an incidental case of ICC with rectal metastasis to investigate its characteristics based on its diagnosis, metastasis, and treatment.