AUTHOR=Zhang Xu , Lu Jianghao , Hao Yanli , Wu Tingting , Gao Zeyan , Zhou Peng TITLE=Case Report: Diagnosis of splenic marginal zone lymphoma by ultrasound and contrast- enhanced ultrasound JOURNAL=Frontiers in Oncology VOLUME=Volume 15 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1569962 DOI=10.3389/fonc.2025.1569962 ISSN=2234-943X ABSTRACT=Early diagnosis of splenic marginal zone lymphoma (SMZL) is difficult because of its insidious symptoms and slow progression. Combining conventional ultrasound with contrast-enhanced ultrasound can enable to differentiate between benign and malignant splenic lesions, which could guide further clinical examination and eventually improve the diagnostic rate of SMZL.