AUTHOR=Lin Yongming , Xie Xinru , Wang Jiayi , Chen Hongbing , Wan Ningning , Lin Jianqing 

TITLE=Case Report: Breast cancer in pregnancy with placental metastasis

JOURNAL=Frontiers in Oncology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1573915

DOI=10.3389/fonc.2025.1573915

ISSN=2234-943X

ABSTRACT=With the increasing incidence of breast malignant tumours in the population, some rare cases of breast cancer have been reported. We would like to share with you a case of placental metastasis of a malignant tumour of the breast: the patient was a young woman who was diagnosed with a breast cancer at 31 weeks of gestation. After regular follow-up, a healthy baby girl was delivered by caesarean section at 37 weeks of pregnancy. In a subsequent placenta specimen, the pathologist found distant metastasis of breast cancer to the placenta. This is rare in distant metastases of breast cancer. The patient is currently undergoing further anti-tumour therapy. Through reviewing the relevant literature, we have compiled and discussed the mechanisms related to the possible use of placenta in preventing cancer invasion and how breast cancer in pregnancy can be followed up. We hope that sharing this case will help further clinical and experimental research.