AUTHOR=Yin Yu-Ting , Gui Chao 

TITLE=Long-term survival of subglottic adenoid cystic carcinoma: a case report

JOURNAL=Frontiers in Oncology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1611107

DOI=10.3389/fonc.2025.1611107

ISSN=2234-943X

ABSTRACT=Adenoid cystic carcinoma of the larynx is rare, mainly localizing in the subglottic region. The clinical presentation is predominantly characterized by dyspnea and hoarseness. In this study, a 38-year-old woman presented symptoms that included hoarseness, wheezing, and coughing. A diagnosis of subglottic adenoid cystic carcinoma was made by laryngoscopy and biopsy and a total laryngectomy was subsequently performed. A decade after the initial surgical intervention, the tumor recurred in the local region. Consequently, a subsequent surgical procedure was undertaken, accompanied by postoperative radiotherapy. A subsequent 5-year follow-up examination revealed no evidence of local recurrence or distant metastasis. Subglottic adenoid cystic carcinoma is an uncommon malignancy. A comprehensive surgical excision can yield a favorable therapeutic outcome. In cases of recurrence, subsequent surgical intervention and postoperative supplemental radiotherapy can achieve positive results.