AUTHOR=Sun Yuxing , Bian Jiangyu , Wang Linfeng , Zhang Tong TITLE=Etoposide and cisplatin in combination with anlotinib for lung NUT carcinoma: a case report JOURNAL=Frontiers in Oncology VOLUME=Volume 15 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1632133 DOI=10.3389/fonc.2025.1632133 ISSN=2234-943X ABSTRACT=Lung NUT carcinoma is a rare malignant tumor, which is highly aggressive, poorly differentiated, and difficult to recognize at an early stage, and is associated with very rare reports and extremely poor prognosis, with some reports showing a mOS of only 2.2 months. In this paper, we report the treatment of a rare case of primary lung NUT cancer. After surgery, chemotherapy and targeted therapy, the patient’s progression-free survival is now more than 4 months, which provides a feasible treatment option for lung NUT cancer.