AUTHOR=Jia Shu-ni , Wang Dong , Xue Ting-ting , Zhao Zhe-xia TITLE=A case report of ectopic breast cancer of the left upper extremity with literature review JOURNAL=Frontiers in Oncology VOLUME=Volume 15 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1674230 DOI=10.3389/fonc.2025.1674230 ISSN=2234-943X ABSTRACT=Ectopic breast cancer (EBC) is a rare type of breast cancer that originates from ectopic breast tissue. This article describes a case with left breast cancer complicated by a second primary breast cancer of the left upper extremity, and summarizes the relevant literature to review the epidemiology, clinical presentation, pathologic features, imaging tests, treatment strategies, and prognosis of EBC with the aim of providing clinicians with a comprehensive reference to improve the understanding and management of this disease.