AUTHOR=Tay John Rong Hao , Chow Dian Yi , Lim Yi Rong Ivan , Ng Ethan 

TITLE=Enhancing patient-centered information on implant dentistry through prompt engineering: a comparison of four large language models

JOURNAL=Frontiers in Oral Health

VOLUME=Volume 6 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/oral-health/articles/10.3389/froh.2025.1566221

DOI=10.3389/froh.2025.1566221

ISSN=2673-4842

ABSTRACT=BackgroundPatients frequently seek dental information online, and generative pre-trained transformers (GPTs) may be a valuable resource. However, the quality of responses based on varying prompt designs has not been evaluated. As dental implant treatment is widely performed, this study aimed to investigate the influence of prompt design on GPT performance in answering commonly asked questions related to dental implants.Materials and methodsThirty commonly asked questions about implant dentistry – covering patient selection, associated risks, peri-implant disease symptoms, treatment for missing teeth, prevention, and prognosis – were posed to four different GPT models with different prompt designs. Responses were recorded and independently appraised by two periodontists across six quality domains.ResultsAll models performed well, with responses classified as good quality. The contextualized model performed worse on treatment-related questions (21.5 ± 3.4, p < 0.05), but outperformed the input-output, zero-shot chain of thought, and instruction-tuned models in citing appropriate sources in its responses (4.1 ± 1.0, p < 0.001). However, responses had less clarity and relevance compared to the other models.ConclusionGPTs can provide accurate, complete, and useful information for questions related to dental implants. While prompt designs can enhance response quality, further refinement is necessary to optimize its performance.