ORIGINAL RESEARCH article
Front. Oral Health
Sec. Oral and Maxillofacial Surgery
Expected Clinical and Patient-Centered Outcomes Associated with Different Rehabilitation Strategies for Severe Maxillary Atrophy: An International Cross-Sectional Survey
- GG
Giulio Gasparini 1
- MT
Mattia Todaro 2
- EP
Edoardo Papa 3
- MG
Marco Gaetano Amato 2
- PD
Paolo De Angelis 4
- AM
Alessandro Moro 2
- CL
Carlo Lajolo 5
- GN
Gianluca Nicolai 3
- ER
Edoardo Rella 6
- RB
Roberto Boniello 2
- XM
Xavier Moix Gil 2
- ES
Edoardo Staderini 7,8
- SG
Sofia Gasparini 9
- FP
Federico Perquoti 2
- GS
Gianmarco Spinozzi 2
- VS
Veronica Santoro 10
- DD
Daniele Di Carlo 2
- GA
Giuliano Ascani 11
- PF
Paolo Francesco Manicone 12
- GS
Gianmarco Saponaro 2
1. Pre-prosthetic surgery Unit, Fondazione Policlinico Agostino Gemelli IRCCS Hospital, Rome, Italy
2. Maxillo-Facial Surgery Unit, IRCSS "A. Gemelli" Foundation-Catholic University of the Sacred Heart, 00168, Rome, Italy
3. Department of Emergency and Acceptance, UOSD maxillofacial surgery, University of Rome Tor Vergata, Rome, Italy
4. Department of Head and Neck, Oral Surgery and Implantology Unit, Institute of Clinical Dentistry, Catholic University of the Sacred Heart, Polyclinic Foundation,, Rome, Italy
5. Head and Neck Department, "Fondazione Policlinico Universitario A. Gemelli - IRCCS," School of Dentistry, Università Cattolica del Sacro Cuore,, Rome, Italy
6. Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore,, Rome, Italy
7. IRCCS, Fondazione Policlinico Universitario Agostino Gemelli, 00168, Rome, Italy
8. Department of Orthodontics, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168, Rome, Italy
9. Pre-prosthetic surgery Unit, Fondazione Policlinico Agostino Gemelli IRCCS Hospital,, Rome, Italy
10. Division of Maxillo-Facial Surgery, Department of Medicine, Surgery and Dentistry, ASST Santi Paolo e Carlo Hospital, University of Milan, Milan, Italy
11. Department of Maxillofacial Surgery, Spirito Santo Hospital, Via Fonte Romana 8, 65124, Pescara, Italy
12. Division of Prosthodontics, Department of Neuroscience, Sensory Organs and Chest, Fondazione Policlinico Universitario A. Gemelli – IRCCS, School of Dentistry, Universita' Cattolica del Sacro Cuore, Rome, Italy
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Abstract
Background Severe maxillary atrophy remains one of the most challenging conditions in implant dentistry and maxillofacial surgery. Multiple rehabilitation strategies are available, including regenerative procedures, alternative implant-based approaches, and hybrid concepts. Although clinical outcomes have been reported, limited information exists regarding clinician-reported expectations associated with different rehabilitation strategies when evaluating the same clinical scenario. The aim of this study was to investigate clinician-reported expectations associated with different rehabilitation approaches for severe maxillary atrophy. Materials and Methods An international cross-sectional survey was conducted using a standardized anonymized CBCT case classified as Cawood and Howell Class VI. The questionnaire was distributed through professional and academic networks between July and November 2025. Respondents with experience in at least five complex implant-prosthetic rehabilitations per year were included. After selecting their preferred rehabilitation strategy, participants completed a branching questionnaire exploring clinician-reported expectations regarding safety, predictability, immediate loading, implant survival, treatment duration, smile satisfaction, masticatory function, oral hygiene and maintainability, postoperative morbidity, annual maintenance costs, patient satisfaction, and quality-of-life improvement. Descriptive statistics were performed. Results A total of 155 eligible clinicians from 33 countries were included. Alternative implant-based strategies were selected by 83 respondents (53.5%), regenerative approaches by 45 (29.0%), and hybrid approaches by 27 (17.4%). Clinicians selecting alternative implant-based strategies more frequently anticipated immediate loading (81.9%), functional rehabilitation within 72 hours (83.1%), and implant survival exceeding 95% at five years (57.8%). Respondents selecting regenerative approaches more commonly expected treatment durations of approximately one year (64.4%) and reported favorable expectations regarding smile satisfaction (86.7%), patient satisfaction (82.2%), and quality-of-life improvement (97.8%). Across all therapeutic preference groups, clinician-reported expectations regarding masticatory function, patient satisfaction, and quality-of-life improvement were favorable. Most respondents anticipated postoperative discomfort lasting between one and four weeks and treatment abandonment rates below 5%. Conclusions Clinicians selecting different rehabilitation strategies for severe maxillary atrophy reported distinct expectations regarding treatment timing, predictability, implant survival, aesthetics, maintenance requirements, morbidity, and patient-outcomes. Despite these differences, expectations were favorable across all therapeutic preference groups, suggesting that multiple rehabilitation pathways are perceived as viable treatment options. The findings should be interpreted as clinician-reported expectations rather than clinical or patient-reported outcomes.
Summary
Keywords
bone grafting, Cawood and Howell Class VI, Clinician preferences, Patient-specific implants (PSI), Pterygoid implants, Severe maxilla atrophy, Treatment decision - making, Zygomatic implants
Received
05 May 2026
Accepted
10 August 2026
Copyright
© 2026 Gasparini, Todaro, Papa, Amato, De Angelis, Moro, Lajolo, Nicolai, Rella, Boniello, Moix Gil, Staderini, Gasparini, Perquoti, Spinozzi, Santoro, Di Carlo, Ascani, Manicone and Saponaro. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Marco Gaetano Amato
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