AUTHOR=Kibret Anteneh Ayelign , Wolde Haileab Fekadu , Moges Abebe Muche , Aragie Hailu , Teferi Ephrem Tafesse , Assefa Yohannes Awoke , Melese Endalkachew Belayneh , Melesse Mequanint , Worku Yilkal Belete , Belay Daniel Gashaneh , Molla Meseret Derbew , Adugna Dagnew Getnet TITLE=Prevalence and associated factors of cancer pain among adult cancer patients evaluated at an oncology unit in the University of Gondar Comprehensive Specialized Hospital, northwest Ethiopia JOURNAL=Frontiers in Pain Research VOLUME=Volume 3 - 2022 YEAR=2023 URL=https://www.frontiersin.org/journals/pain-research/articles/10.3389/fpain.2022.1061239 DOI=10.3389/fpain.2022.1061239 ISSN=2673-561X ABSTRACT=Abstract Introduction: Globally, cancer is the second leading cause of death and is responsible for the occurrence of 9.6 million deaths. Worldwide, two million people suffer from pain every day and cancer pain is one of the major neglected public health problems, especially in Ethiopia. Despite reporting the burden and risk factors of cancer pain has principal importance, there is limited study. Therefore, this study aimed to assess the prevalence of cancer pain and associated factors among adult patients evaluated at the Oncology ward, in the University of Gondar Comprehensive Specialized Hospital (UoGCSH), Northwest Ethiopia. Methods: Institution-based cross-sectional study was conducted from January 1 to March 31, 2021. Systematic random sampling technique was used to select the total sample size of 384 patients. Data were collected using pretested and structured interviewer-administered questionnaire. Bivariate and multivariate logistic regression model was fitted to identify factors associated with cancer pain among cancer patients. An adjusted odds ratio with 95% confidence interval was computed to determine the level of significance. Result: A total of 384 study participants were involved with a response rate of 97.5%. The proportion of cancer pain was found to be 59.9% (95%CI: 54.8, 64.8). The odds of cancer pain was escalated by anxiety [AOR = 2.52; 95%CI: 1.02, 6.19], patients with hematological cancer [AOR = 4.68, 95%CI: 1.30, 16.74], gastrointestinal cancer [AOR = 5.15, 95%CI: 1.45, 18.2], and stage III and IV [AOR = 14.3; 95%CI: 3.20, 63.7] Conclusion: The prevalence of cancer pain among adult cancer patients in Northwest Ethiopia is relatively high. Variables such as anxiety, types of cancer, and stage of cancer had a statistically significant association with cancer pain. Hence, to advance the management of pain, better to create more awareness regarding cancer-related pain and provide a palliative care early-on in diagnosis of disease.