AUTHOR=Rideout Hannah , Cook Alasdair J. C. , Whetton Anthony D. TITLE=Understanding the Cryptosporidium species and their challenges to animal health and livestock species for informed development of new, specific treatment strategies JOURNAL=Frontiers in Parasitology VOLUME=Volume 3 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/parasitology/articles/10.3389/fpara.2024.1448076 DOI=10.3389/fpara.2024.1448076 ISSN=2813-2424 ABSTRACT=

Cryptosporidium species are parasitic organisms of vertebrates with a worldwide distribution. They have an important impact globally upon human and animal health, and livestock productivity. The life cycle of these species is complex and difficult to disrupt to improve human health, animal health, food security and economic growth. This may contribute to the fact that no new treatment strategy has been widely accepted or applied in livestock for years. Here we consider the natural history of these parasites, their biochemistry and economic impact. Using recent developments in understanding these parasites we then consider viable and affordable approaches to enhancing control of their effects on livestock. These are based on advances in drug discovery, omics research and artificial intelligence applications to human and veterinary medicine that indicate putative new therapeutic approaches.