AUTHOR=Jansen Marleen E. , Klein Anne W. , Buitenhuis Erika C. , Rodenburg Wendy , Cornel Martina C. 

TITLE=Expanded Neonatal Bloodspot Screening Programmes: An Evaluation Framework to Discuss New Conditions With Stakeholders

JOURNAL=Frontiers in Pediatrics

VOLUME=Volume 9 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2021.635353

DOI=10.3389/fped.2021.635353

ISSN=2296-2360

ABSTRACT=	Neonatal bloodspot screening (NBS) programmes that screen for rare but serious conditions are expanding worldwide.
	Fast developments for testing and treatment put pressure on implementation processes.
	In 2015 the Netherlands embarked on an NBS expansion from seventeen to thirty-one conditions. 
	An evaluation framework was developed based on international NBS frameworks to gain insight in test properties, clinical findings, follow-up and implementation.
	A stakeholder process took place with implications for the planning of the expanded NBS panel. 
	The evaluation framework progressed into a go / no go framework to start national screening, and is currently explored as basis for continuous evaluation of the NBS panel.
	The framework and stakeholder process may serve as an example for other programmes.