AUTHOR=Chao Liu , Lei Zhang , Xiang Li , Qi Zhou 

TITLE=Pediatric unicystic cystic partially differentiated nephroblastoma: The first case report

JOURNAL=Frontiers in Pediatrics

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2022.1045936

DOI=10.3389/fped.2022.1045936

ISSN=2296-2360

ABSTRACT=Cystic partially differentiated nephroblastoma (CPDN) has been reported to date, all of which present as polycystic renal tumor. It is a special pathological type of nephroblastoma. Here we report the first case of unicystic CPDN in children. The patient was diagnosed as simple renal cyst and underwent laparoscopic decortication. The naive nephron was found in the pathological section and the diagnosis of CPDN was confirmed. The patient then underwent radical nephrectomy and six cycles of postoperative chemotherapy. There was no recurrence or metastasis after 2 years of follow-up. Pediatric CPDN presenting as an unicystic renal tumor poses a new challenge to the diagnosis, differential diagnosis and treatment of unicystic renal tumor.