AUTHOR=Abhay Pota , Sharma Rajesh , Bhan Anil , Raina Manan , Vadhera Ananya , Akole Romel , Mir Firdoos Ahmad , Bajpai Pankaj , Misri Amit , Srivastava Swarnika , Prakash Ved , Mondal Tanmoy , Soundararajan Anvitha , Tibrewal Abhishek , Bansal Shyam Bihari , Sethi Sidharth Kumar 

TITLE=Vasoactive-ventilation-renal score and outcomes in infants and children after cardiac surgery

JOURNAL=Frontiers in Pediatrics

VOLUME=Volume 11 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1086626

DOI=10.3389/fped.2023.1086626

ISSN=2296-2360

ABSTRACT=Introduction: There is a need to index important clinical characteristics in pediatric cardiac surgery that can be obtained early in the postoperative period and accurately predict postoperative outcomes. 

Methodology: A prospective cohort study was conducted in pediatric cardiac ICU and ward on all children <18 years undergoing cardiac surgery for congenital heart disease from 9/2018-10/2020. Vasoactive-Ventilation-Renal (VVR) score was analyzed to predict outcomes of cardiac surgeries with comparison of post-operative variables. 

Results: A total of 199 children underwent cardiac surgery during the study period. The median (IQR) age was 2 (0.8-5) years and weight was 9.3 (6-16) kg. The most common diagnoses were ventricular sep¬tal defect (46.2%) and Tetralogy of Fallot (37.2%). At 48th hour, AUC (95% CI) values were higher for VVR score than other clinical scores measured. Similarly, at 48th hour, AUC (95% CI) values were higher for VVR score than other clinical scores measured for length of stay and mechanical ventilation. 

Discussion: The VVR score at 48 hours post-operation was found to best correlate with prolonged PICU stay, length of hospitalization and ventilation duration with the greatest AUC-ROC (0.715, 0.723, and 0.843, respectively). 48-hour VVR score correlates well with prolonged ICU, hospital stay and ventilation.