AUTHOR=Bekelman Traci A. , Trasande Leonardo , Law Andrew , Blackwell Courtney K. , Jacobson Lisa P. , Bastain Theresa M. , Breton Carrie V. , Elliott Amy J. , Ferrara Assiamira , Karagas Margaret R. , Aschner Judy L. , Bornkamp Nicole , Camargo Carlos A. , Comstock Sarah S. , Dunlop Anne L. , Ganiban Jody M. , Gern James E. , Karr Catherine J. , Kelly Rachel S. , Lyall Kristen , O’Shea T. Michael , Schweitzer Julie B. , LeWinn Kaja Z. TITLE=Opportunities for understanding the COVID-19 pandemic and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) program JOURNAL=Frontiers in Pediatrics VOLUME=Volume 11 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1171214 DOI=10.3389/fped.2023.1171214 ISSN=2296-2360 ABSTRACT=Objective

Ongoing pediatric cohort studies offer opportunities to investigate the impact of the COVID-19 pandemic on children's health. With well-characterized data from tens of thousands of US children, the Environmental influences on Child Health Outcomes (ECHO) Program offers such an opportunity.

Methods

ECHO enrolled children and their caregivers from community- and clinic-based pediatric cohort studies. Extant data from each of the cohorts were pooled and harmonized. In 2019, cohorts began collecting data under a common protocol, and data collection is ongoing with a focus on early life environmental exposures and five child health domains: birth outcomes, neurodevelopment, obesity, respiratory, and positive health. In April of 2020, ECHO began collecting a questionnaire designed to assess COVID-19 infection and the pandemic's impact on families. We describe and summarize the characteristics of children who participated in the ECHO Program during the COVID-19 pandemic and novel opportunities for scientific advancement.

Results

This sample (n = 13,725) was diverse by child age (31% early childhood, 41% middle childhood, and 16% adolescence up to age 21), sex (49% female), race (64% White, 15% Black, 3% Asian, 2% American Indian or Alaska Native, <1% Native Hawaiian or Pacific Islander, 10% Multiple race and 2% Other race), Hispanic ethnicity (22% Hispanic), and were similarly distributed across the four United States Census regions and Puerto Rico.

Conclusion

ECHO data collected during the pandemic can be used to conduct solution-oriented research to inform the development of programs and policies to support child health during the pandemic and in the post-pandemic era.