AUTHOR=Adaikina Alena , Derraik José G. B. , McMillan Janene , Colle Patricia , Hofman Paul L. , Gusso Silmara TITLE=Feasibility study on a longer side-alternating vibration therapy protocol (15 min per session) in children and adolescents with mild cerebral palsy JOURNAL=Frontiers in Pediatrics VOLUME=Volume 11 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1231068 DOI=10.3389/fped.2023.1231068 ISSN=2296-2360 ABSTRACT=Objective: Previous studies on side-alternating vibration therapy (sVT) have usually used a 9-minute intervention protocol. We performed a feasibility study aimed at assessing the safety, acceptability, and potential effectiveness of a longer sVT protocol (15-minute per session) in children and adolescents with cerebral palsy (CP).Methods: Fifteen participants aged 5.2-17.4 years (median=12.4 years) with CP GMFCS level II underwent 20 weeks of sVT consisting of 15-minute sessions 4 days/week. Participants were assessed at baseline and after the intervention period, including mobility (six-minute walk-test; 6MWT), body composition (whole-body dual-energy X-ray absorptiometry scans), and muscle function (force plate).Results: Adherence level to the 15-min VT protocol was 83% on average. There were no adverse events reported. After 20 weeks, there was some evidence for an increase in the walking distance covered in 6MWT (+43 m; p=0.0018) and spine bone mineral density (+0.032 g/cm 2 ; p=0.012) compared to baseline.The 15-minute sVT protocol is feasible and well tolerated. The results also suggest potential benefits of this protocol to mobility and bone health. Randomized controlled trials are needed to reliably ascertain the potential effectiveness of a longer sVT protocol on physical function and body composition in young people with CP.