AUTHOR=Orozco Morales José Antonio , Medina Urrutia Aída Xochitl , Tamayo Margarita Torres , Reyes Barrera Juan , Galarza Esteban Jorge , Juárez Rojas Juan Gabriel , Dies Suarez Pilar , Méndez Sánchez Nahum , Díaz Orozco Luis Enrique , Velázquez-López Lubia , Medina Bravo Patricia 

TITLE=Impact of metabolic-associated fatty liver disease on the cholesterol efflux capacity of high-density lipoproteins in adolescents with type 2 diabetes

JOURNAL=Frontiers in Pediatrics

VOLUME=Volume 12 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2024.1462406

DOI=10.3389/fped.2024.1462406

ISSN=2296-2360

ABSTRACT=Context: Type 2 diabetes (DM2) is an emerging disease in the pediatric population. DM2 is associated with metabolic-associated fatty liver disease (MAFLD). High-density lipoproteins (HDLs) are lipoproteins that are believed to have atheroprotective properties that reduce the risk of cardiovascular disease (CVD). Current evidence suggests that the physicochemical and functional features of HDLs may play a key role in the pathogenesis of atherosclerosis.Objective: We aimed to assess the impact of MAFLD on cholesterol efflux capacity (CEC) in adolescents with DM2.