AUTHOR=Zhang Liwen , Yang Guijun , Yuan Jiajun , Yuan Shuhua , Zhang Jing , Chen Jiande , Tang Mingyu , Zhang Yunqin , Lin Jilei , Zhao Liebin , Yin Yong TITLE=Enhancing pediatric asthma management in underdeveloped regions through ChatGPT training for doctors: a randomized controlled trial JOURNAL=Frontiers in Pediatrics VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1519751 DOI=10.3389/fped.2025.1519751 ISSN=2296-2360 ABSTRACT=BackgroundChildhood asthma represents a significant challenge globally, especially in underdeveloped regions. Recent advancements in Large Language Models (LLMs), such as ChatGPT, offer promising improvements in medical service quality.MethodsThis randomized controlled trial assessed the effectiveness of ChatGPT in enhancing physicians' childhood asthma management skills. A total of 192 doctors from varied healthcare environments in China were divided into a control group, receiving traditional medical literature training, and an intervention group, trained in utilizing ChatGPT. Assessments conducted before and after training, and a 2-week follow-up, measured the training's impact.ResultsThe intervention group showed significant improvement, with scores of test questions increasing by approximately 20 out of 100 (improving to 72 ± 8 from a baseline, vs. the control group's increase to 50 ± 9). Post-training, ChatGPT's regular usage among the intervention group jumped from 6.3% to 62%, markedly above the control group's 4.3%. Moreover, physicians in the intervention group reported higher levels of familiarity, effectiveness, satisfaction, and intention for future use of ChatGPT.ConclusionChatGPT training significantly improves childhood asthma management among physicians in underdeveloped regions. This underscores the utility of LLMs like ChatGPT as effective educational tools in medical training, highlighting the need for further research into their integration and patient outcome impacts.