AUTHOR=Hussein Hussein , Paget Richard , Grandjean Louis , Bamford Alasdair , Pandey Ashwin , Fidler Katy , Snowden Claire , Beeman Arun , Shetty Pooja , Muthialu Nagarajan TITLE=Case Report: Use of extracorporeal support to treat a fulminant Mycobacterium bovis infection and complex broncho-oesophageal fistula in a child JOURNAL=Frontiers in Pediatrics VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1559240 DOI=10.3389/fped.2025.1559240 ISSN=2296-2360 ABSTRACT=Tuberculosis (TB), caused by Mycobacterium tuberculosis remains a significant public health issue. Human TB caused by Mycobacterium bovis (M. bovis) is rare accounting for less than 1% of TB cases in UK annually. Tuberculosis secondary to immunomodulating agents is well described. We present a case of airway and pulmonary TB caused by M. bovis, likely due to zoonotic transmission, in an immunocompromised child due to medical management of Crohn's disease. Management required extracorporeal membrane oxygenation for complex surgical interventions on airway and oesophagus.