AUTHOR=Lopes Nailu Lealina Garrido , Amaral Vivian Henriques do , Minozzi Marina Simões , Guazzelli Pitta Madureira Paola , Zagne Braz Luisa , da Hora Passos Rogerio TITLE=Lung ultrasound in the management of mechanical ventilation in pediatric critical care: a narrative review JOURNAL=Frontiers in Pediatrics VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2025.1630918 DOI=10.3389/fped.2025.1630918 ISSN=2296-2360 ABSTRACT=Lung ultrasound (LUS) has become an increasingly valuable tool in the management of critically ill pediatric patients, offering dynamic, radiation-free bedside evaluation of pulmonary function. This narrative review synthesizes current evidence on the application of LUS in the context of ventilation in children and neonates. Key domains include its role in determining the indication for ventilation, guiding ventilatory adjustments, assessing positive end-expiratory pressure (PEEP) response, supporting lung recruitment maneuvers, and aiding in weaning and extubation decisions. The use of LUS in diagnosing ventilator-associated pneumonia (VAP) is also addressed, highlighting characteristic sonographic findings and their limitations. The I-VENT mnemonic is proposed as a practical framework for clinicians to integrate LUS into ventilatory management. While further research is needed to standardize protocols and validate scoring systems, current evidence supports the routine use of LUS in pediatric intensive care as a safe, accessible, and informative tool for optimizing respiratory support.