https://www.frontiersin.org/journals/pediatrics RSS Feed for Frontiers in Pediatrics | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-04-16T12:44:47.814+00:00 60 https://www.frontiersin.org/articles/10.3389/fped.2026.1739376 https://www.frontiersin.org/articles/10.3389/fped.2026.1739376 2026-04-16T00:00:00Z Review Yubing WangZhifei ZhaoJinbin WangShujie SongChengmin ZhaoChao QvHongting Lu https://www.frontiersin.org/articles/10.3389/fped.2026.1809311 https://www.frontiersin.org/articles/10.3389/fped.2026.1809311 2026-04-16T00:00:00Z Case Report Wenkai YangQian RenBowen Li https://www.frontiersin.org/articles/10.3389/fped.2026.1774350 https://www.frontiersin.org/articles/10.3389/fped.2026.1774350 2026-04-16T00:00:00Z Original Research Hongyi CaiWenyong WuXin YuanYing ZhangXiaohong YangXiaozhen HuangZhuanzhuan AiDandan LiRuimin Chen  0.05). BMI increased significantly in both groups (quarterly: from 16.96 ± 2.10 to 17.89 ± 2.53 kg/m2, P = 0.01; monthly: from 16.89 ± 2.06 to 17.50 ± 2.03 kg/m2, P = 0.008), with no significant differences between regimens. Three patients experiencing a “flare-up” had a larger mean baseline uterine volume (6.95 mL) compared with the remaining 67 patients (2.38 mL).ConclusionQuarterly triptorelin demonstrated efficacy comparable to that of monthly administration in suppressing puberty and improving PAH in Chinese girls with CPP.]]> https://www.frontiersin.org/articles/10.3389/fped.2026.1761634 https://www.frontiersin.org/articles/10.3389/fped.2026.1761634 2026-04-15T00:00:00Z Original Research Abdulelah A. OtaifRamzi M. DighririAbdulrahman A. OtaifRiyadh A. JahlanOsama A. AlotayfAli Y. ShaikhSaud N. AlwadaniRaghad M. AlnamiAsma M. Soweedi https://www.frontiersin.org/articles/10.3389/fped.2026.1774544 https://www.frontiersin.org/articles/10.3389/fped.2026.1774544 2026-04-15T00:00:00Z Original Research Ping WangJian Li 24 h) (Z = −3.874 and −4.125, respectively, both P < 0.001). Co-detection of EBV and abnormal liver function were associated with a significant prolongation of hospital stay (Z = −3.987 and −4.563, respectively, both P < 0.001).ConclusionHSV is a frequently isolated pathogen in febrile infants and young children with herpetic gingivostomatitis as the core clinical diagnosis and diverse clinical manifestations dominated by non-specific systemic and oropharyngeal symptoms (cutaneous herpes with low incidence). HSV infection is often accompanied by co-detection of other pathogens such as EBV and Bordetella pertussis (diagnosed by standardized serological, PCR and microbial culture methods) and abnormal liver function in some cases. Early HSV-PCR detection combined with serological testing, timely and individualized acyclovir treatment (with clear course standards) based on comprehensive clinical judgment can significantly improve the clinical outcomes of febrile children with HSV detected. Comprehensive intervention targeting co-detected pathogens and complications is equally important for the clinical management of such cases.]]> https://www.frontiersin.org/articles/10.3389/fped.2026.1727430 https://www.frontiersin.org/articles/10.3389/fped.2026.1727430 2026-04-15T00:00:00Z Original Research Shengfeng SunMingqi WangShuyan YangYuanyuan Huang 1 × 105 copies/mL, and total iron-binding capacity(TIBC) were detected(all P < 0.05). Multivariate logistic regression analysis revealed that TIBC and whole blood EBV DNA load >1 × 105 copies/mL were risk factors, whereas the PLR was a protective factor. ROC curve analysis showed that the cutoff values of TIBC and reciprocal platelet-to-lymphocyte ratio (rPLR) for the diagnosis of EBV-IM-related hepatic injury were 53.250 μmol/L and 0.052, with areas under the curve of 0.652 and 0.713, sensitivities of 69.2% and 53.8%, and specificities of 62.7% and 88.2%, and these two indicators could be used as diagnostic markers for hepatic injury in children with EBV-IM.ConclusionEBV-IM-related hepatic injury in children correlates with iron metabolism. TIBC and whole blood EBV DNA load (>1 × 105 copies/mL) are independent risk factors, whereas the PLR is a protective factor.]]> https://www.frontiersin.org/articles/10.3389/fped.2026.1838282 https://www.frontiersin.org/articles/10.3389/fped.2026.1838282 2026-04-15T00:00:00Z Correction Eun Song SongEun Mi Yang https://www.frontiersin.org/articles/10.3389/fped.2026.1809021 https://www.frontiersin.org/articles/10.3389/fped.2026.1809021 2026-04-15T00:00:00Z Case Report Jiaqi LiLiting HouQianqian LiuBin YanWeikai WangHongxia Gao https://www.frontiersin.org/articles/10.3389/fped.2026.1785969 https://www.frontiersin.org/articles/10.3389/fped.2026.1785969 2026-04-15T00:00:00Z Original Research Qirui LiuMengzhen ZhangHao WeiAilian Wang https://www.frontiersin.org/articles/10.3389/fped.2026.1803924 https://www.frontiersin.org/articles/10.3389/fped.2026.1803924 2026-04-15T00:00:00Z Case Report Minerva Montero-HernándezNahuel Pérez-MoixMaría-Carmen Carrascosa-RomeroMaría-Pilar López-GarridoFrancisco Sánchez-Sánchez https://www.frontiersin.org/articles/10.3389/fped.2026.1799664 https://www.frontiersin.org/articles/10.3389/fped.2026.1799664 2026-04-15T00:00:00Z Case Report Shuyu LiuChi MaCangming ShiDawei Chen https://www.frontiersin.org/articles/10.3389/fped.2026.1713890 https://www.frontiersin.org/articles/10.3389/fped.2026.1713890 2026-04-15T00:00:00Z Case Report Simone CoslovichMatteo BramuzzoSerena PastoreDaniela ChiccoSara LegaGiulia GortaniThomas CaiffaAlberto TommasiniAndrea Taddio https://www.frontiersin.org/articles/10.3389/fped.2026.1795907 https://www.frontiersin.org/articles/10.3389/fped.2026.1795907 2026-04-15T00:00:00Z Original Research Aya M. BaageelShahad M. AldiniTuleen J. AbudawoodHanin H. Rayes https://www.frontiersin.org/articles/10.3389/fped.2026.1631683 https://www.frontiersin.org/articles/10.3389/fped.2026.1631683 2026-04-15T00:00:00Z Case Report Linlin ChenJie LiXixi LiuXiyang ChenHaiting LiDengpan XieYunqin ChenJunhui YuanEnfu Tao https://www.frontiersin.org/articles/10.3389/fped.2026.1794686 https://www.frontiersin.org/articles/10.3389/fped.2026.1794686 2026-04-15T00:00:00Z Case Report Zhong YongxingZhang ZhengZheng QiYang Fangyan https://www.frontiersin.org/articles/10.3389/fped.2026.1739614 https://www.frontiersin.org/articles/10.3389/fped.2026.1739614 2026-04-15T00:00:00Z Original Research Rebecca Orsi-HuntHeather AllanRachel A. WilsonGretchen DomekBrooks R. KeeshinAmanda Bird Hoffert Gilmartin https://www.frontiersin.org/articles/10.3389/fped.2026.1785074 https://www.frontiersin.org/articles/10.3389/fped.2026.1785074 2026-04-15T00:00:00Z Original Research Lexi NussbaumYotham A. GwanikaPrisca Joseph StephanoHappiness D. KajokaCatherine StatonHenry E. RiceBlandina T. MmbagaEmily R. SmithPamela EspinozaEsther Majaliwa https://www.frontiersin.org/articles/10.3389/fped.2026.1758972 https://www.frontiersin.org/articles/10.3389/fped.2026.1758972 2026-04-15T00:00:00Z Original Research Renée LampeIrina SidorenkoEva LückAndrey KovtanyukUrsula Felderhoff-MüserMarcus KrügerChristian Brickmann https://www.frontiersin.org/articles/10.3389/fped.2026.1774627 https://www.frontiersin.org/articles/10.3389/fped.2026.1774627 2026-04-15T00:00:00Z Original Research Mengqin ShanChaoyang TongXin FuYuxin ZhangLiping SunKan ZhangJijian Zheng https://www.frontiersin.org/articles/10.3389/fped.2026.1767283 https://www.frontiersin.org/articles/10.3389/fped.2026.1767283 2026-04-15T00:00:00Z Original Research Wenyan WangFei ZhaoGuixia DingSanlong ZhaoGuoliang MaXueqin Cheng  0.05).ConclusionRepeat kidney biopsy detects pathological progression (e.g., increased chronicity) and guides treatment modifications in over 60% of pediatric LN cases. However, pathological class change alone does not dictate short-term outcomes, highlighting initial treatment response as a stronger prognostic indicator. Individualized use of repeat biopsies is recommended for children with proteinuria relapse to optimize management while mitigating procedural invasiveness.]]>