Frontiers in Pediatrics | New and Recent Articles https://www.frontiersin.org/journals/pediatrics RSS Feed for Frontiers in Pediatrics | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-05-08T04:17:51.916+00:00 60 https://www.frontiersin.org/articles/10.3389/fped.2026.1762616 https://www.frontiersin.org/articles/10.3389/fped.2026.1762616 <![CDATA[Case Report: Progressive limb necrosis as a portal to multifocal osteomyelitis in pediatric septic shock: a tissue-oriented management paradigm]]> 2026-05-08T00:00:00Z Case Report Cheng YangWansha ZhouXimeng HuangJiawei Li https://www.frontiersin.org/articles/10.3389/fped.2026.1746048 https://www.frontiersin.org/articles/10.3389/fped.2026.1746048 <![CDATA[Neonatal-onset dilated cardiomyopathy as the initial manifestation of Alström syndrome: a case report]]> 2026-05-07T00:00:00Z Case Report Hua WangWandong MaJingshi ChenBo Li https://www.frontiersin.org/articles/10.3389/fped.2026.1826300 https://www.frontiersin.org/articles/10.3389/fped.2026.1826300 <![CDATA[Feasibility and safety of endoscopic retrograde appendiceal foreign body removal in children]]> 2026-05-07T00:00:00Z Original Research Tianjiao GaoKuku GeLina SunBianhua LiuDan NanZhao YangYing FangXiaoxia Ren https://www.frontiersin.org/articles/10.3389/fped.2026.1818666 https://www.frontiersin.org/articles/10.3389/fped.2026.1818666 <![CDATA[Procedural pain in pediatric care: educational, ethical, and public health imperatives]]> 2026-05-07T00:00:00Z Opinion Christoffer KrugMichael KnipperPhilipp Stieger https://www.frontiersin.org/articles/10.3389/fped.2026.1817016 https://www.frontiersin.org/articles/10.3389/fped.2026.1817016 <![CDATA[A clustered pulmonary Tuberculosis outbreak at a technical school in Shenzhen, China]]> 2026-05-07T00:00:00Z Original Research Jing TangMingbin XieCongyang LiFan HuangLiai PengYali QuJinzhou MeiZhenyang LiuEryong LiuYanfang GuoYunxia Wang https://www.frontiersin.org/articles/10.3389/fped.2026.1792500 https://www.frontiersin.org/articles/10.3389/fped.2026.1792500 <![CDATA[Ophthalmologic assessment and intracranial pressure in children: diagnostic methods, clinical correlations, and future directions]]> 2026-05-07T00:00:00Z Review Elena Hernández-GarcíaBarbara Burgos-BlascoNoemi Güemes-VillahozLaura Morales-FernandezJose Ignacio Fernandez-VigoEnrique Santos-BuesoRosario Gomez-de-LiañoJulian García-Feijóo https://www.frontiersin.org/articles/10.3389/fped.2026.1815201 https://www.frontiersin.org/articles/10.3389/fped.2026.1815201 <![CDATA[Association between a four-locus gene model including IL13, IL4, FCER1B, and ADRB2 and asthma outcomes]]> 2026-05-07T00:00:00Z Original Research Shasha BaiLinlin QinTingting ZhouShaomin ChenFen YangLi HuaYixiao Bao https://www.frontiersin.org/articles/10.3389/fped.2026.1794811 https://www.frontiersin.org/articles/10.3389/fped.2026.1794811 <![CDATA[Multi-omics integration reveals BPGM downregulation and potential plasma metabolite biomarkers for childhood asthma]]> 2026-05-07T00:00:00Z Original Research Junlin ZhaoZhiyuan WangYanan WangQianqian DaiMenghua LiAliya MaimaitiniyaziZhenzhen GuoLiang Ru  0.25), including significant BPGM downregulation (log2FC = −0.2731, p = 0.0422). Metabolomics revealed 516 differential metabolites [p < 0.05, variable importance in projection (VIP) > 1]. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway intersection identified glycine-serine-threonine metabolism (hsa00260) as the core shared pathway, enriched with BPGM and three upregulated metabolites: L-tryptophan, 5-aminolevulinic acid, and L-aspartate semialdehyde. These metabolites demonstrated good diagnostic performance with area under the curve (AUC) values of 0.818, 0.844, and 0.818, respectively. 5-Aminolevulinic acid showed optimal diagnostic accuracy with 80% sensitivity and 80% specificity. Spearman correlation analysis revealed that 5-aminolevulinic acid was significantly positively correlated with both serum IgE (r = 0.469, p = 0.009) and eosinophil counts (r = 0.506, p = 0.004), while no significant correlations were observed with pulmonary function parameters.ConclusionsThis preliminary multi-omics integration study identified concurrent BPGM downregulation and altered glycine-serine-threonine metabolism in childhood asthma. While these findings suggest a potential association between BPGM expression changes and metabolic alterations in this pathway, the proposed mechanistic link remains hypothetical and requires direct experimental validation.]]> https://www.frontiersin.org/articles/10.3389/fped.2026.1820131 https://www.frontiersin.org/articles/10.3389/fped.2026.1820131 <![CDATA[Sense of coherence in family caregivers of children with chronic diseases: a narrative review]]> 2026-05-07T00:00:00Z Mini Review Fangyu ShiJunjie ZhaoXin Zhang https://www.frontiersin.org/articles/10.3389/fped.2026.1732453 https://www.frontiersin.org/articles/10.3389/fped.2026.1732453 <![CDATA[Case Report: BKV-specific T cells: a fast, safe and potentially effective treatment option for refractory BKV infections in pediatric patients after allogeneic stem cell transplantation]]> 2026-05-07T00:00:00Z Case Report Sven OberwegnerSteffen A. HettlerLuca HensenAmadeus T. HeinzChristiane BraunMichaela DöringPeter Lang https://www.frontiersin.org/articles/10.3389/fped.2026.1805856 https://www.frontiersin.org/articles/10.3389/fped.2026.1805856 <![CDATA[Prenatal ultrasound diagnosis, intrauterine monitoring and postnatal management of a giant fetal abdominopelvic lymphangioma: a case report and scoping review]]> 2026-05-07T00:00:00Z Case Report Matteo GiudiceMilena ViggianoChiara VassalloAlice NovakLaura ValfrèIrma CapolupoAndrea DottaAndrea ConfortiMarco BonitoMaurizio GuidaLeonardo CaforioIsabella Fabietti https://www.frontiersin.org/articles/10.3389/fped.2026.1834587 https://www.frontiersin.org/articles/10.3389/fped.2026.1834587 <![CDATA[Commentary: A rare case report of Salmonella infection: severe necrotizing pneumonia with empyema in an immunocompetent child]]> 2026-05-04T00:00:00Z General Commentary Regina Célia de Souza Campos FernandesEnrique Medina-Acosta https://www.frontiersin.org/articles/10.3389/fped.2026.1812750 https://www.frontiersin.org/articles/10.3389/fped.2026.1812750 <![CDATA[Gastroenterologically relevant high alert medications prescribed to children with chronic diseases—a consensus-driven single-center pilot study]]> 2026-05-04T00:00:00Z Brief Research Report Judith HochrainerRebecca EinspielerAndreas HeilosJudith PichlerMichael Boehm https://www.frontiersin.org/articles/10.3389/fped.2026.1784387 https://www.frontiersin.org/articles/10.3389/fped.2026.1784387 <![CDATA[Merging evans syndrome with mucopolysaccharidosis type II: a case report]]> 2026-05-04T00:00:00Z Case Report Xinrui WangJing ZhangYanhui TangChunyan LiuPeng HuYou YangHongying Chen https://www.frontiersin.org/articles/10.3389/fped.2026.1759935 https://www.frontiersin.org/articles/10.3389/fped.2026.1759935 <![CDATA[A literature review: progress in the study of plastic bronchitis]]> 2026-05-04T00:00:00Z Review Huihan LiChi HanDanchen WuYuanyuan Zhang https://www.frontiersin.org/articles/10.3389/fped.2026.1807879 https://www.frontiersin.org/articles/10.3389/fped.2026.1807879 <![CDATA[Intubation in children presenting with seizures to a pediatric emergency department in a safety net hospital]]> 2026-05-04T00:00:00Z Original Research Mugdha MohantyZakir ShaikhHovra ZahoorShivangi KatariaN. Paul RosmanAlcy R. Torres https://www.frontiersin.org/articles/10.3389/fped.2026.1811557 https://www.frontiersin.org/articles/10.3389/fped.2026.1811557 <![CDATA[Case Report: Atypical presentations of neonatal and infantile hemophilia B]]> 2026-05-04T00:00:00Z Case Report Arielle LockeNasrin SamjiMihir BhattKay DeckerSara J. IsraelsAnthony K. C. ChanKyle Mendonça https://www.frontiersin.org/articles/10.3389/fped.2026.1779116 https://www.frontiersin.org/articles/10.3389/fped.2026.1779116 <![CDATA[Machine learning-based identification of inflammatory biomarkers for predicting pulmonary consolidation in children with Chlamydia pneumoniae infection]]> 2026-05-04T00:00:00Z Original Research Qianqian DaiZhiyuan WangJunlin ZhaoYanan WangMenghua LiAliya MaimaitiniyaziXueli WangJianjiang CuiZhenzhen GuoShengmeng QuWen ZhaoLiang Ru https://www.frontiersin.org/articles/10.3389/fped.2026.1752616 https://www.frontiersin.org/articles/10.3389/fped.2026.1752616 <![CDATA[Systemic propranolol and topical moist wound dressings for ulcerated infantile hemangioma of the scrotum: a case report]]> 2026-05-04T00:00:00Z Case Report Jiejun XiaKunshan ChenZhenyin LiuXiaoyun TanShifeng XieHaibo Li https://www.frontiersin.org/articles/10.3389/fped.2026.1799724 https://www.frontiersin.org/articles/10.3389/fped.2026.1799724 <![CDATA[RSV-infected children with mixed infections: clinical features and early predictive indicators of codetection with Streptococcus pneumoniae and Haemophilus influenzae]]> 2026-05-04T00:00:00Z Original Research Jingwen NiJunyu DongLele LiMengxin ZhaoZhihui DuJie LiKenan FangKai-Sheng Hsieh