AUTHOR=Xie Lei , Bourne Philip E. TITLE=Developing multi-target therapeutics to fine-tune the evolutionary dynamics of the cancer ecosystem JOURNAL=Frontiers in Pharmacology VOLUME=6 YEAR=2015 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2015.00209 DOI=10.3389/fphar.2015.00209 ISSN=1663-9812